dbPTM

VP221_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VP221_ARATH
UniProt AC	Q5M759
Protein Name	Vacuolar protein sorting-associated protein 22 homolog 1
Gene Name	VP22-1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	250
Subcellular Localization	Endosome.
Protein Description	Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex (By similarity)..
Protein Sequence	MRRRPGIGGLQKAAAARDQYRLLGENVAKLRTDMMKEQLSTFRSQLEEFARKHKNDIRKNPAFRAQFHEMCANIGVDPLASNKGFWAELLGIGDFYYELGVQIIEVCMLTRSHNGGLISLQELCNHLRQRRKKDREAVTEDDCLRAISKLKVLGSGFEVITIGKKKLVRSVPTELNKDHNQILELAQGQGFVIVEEVQRRLSWTSGRVIDALETLLEEGLAMIDNGHKDGKCRYWFPCVSSVYSSIGSDT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of VP221_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VP221_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VP221_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VP221_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELC_ARATH	ELC	physical	21442383
ELCL_ARATH	ELC-Like	physical	21442383
VP282_ARATH	VPS28-2	physical	21442383
VPS36_ARATH	AT5G04920	physical	21442383
ELC_ARATH	ELC	physical	22639582
ELCL_ARATH	ELC-Like	physical	22639582
VP221_ARATH	VPS22	physical	22639582
VPS25_ARATH	VPS25	physical	22639582
VPS36_ARATH	AT5G04920	physical	22639582

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VP221_ARATH

Related Literatures of Post-Translational Modification