dbPTM

ELC_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ELC_ARATH
UniProt AC	Q9LHG8
Protein Name	Protein ELC {ECO:0000303\|PubMed:17090720}
Gene Name	ELC {ECO:0000303\|PubMed:17090720}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	398
Subcellular Localization	Early endosome . Late endosome . Prevacuolar compartment .
Protein Description	Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). May control nuclear division through the microtubule cytoskeleton..
Protein Sequence	MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of ELC_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ELC_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ELC_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ELC_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VP372_ARATH	AT2G36680	physical	17090720
VP281_ARATH	VPS28-1	physical	17090720
ELC_ARATH	ELC	physical	21442383
ELCL_ARATH	ELC-Like	physical	21442383
VP371_ARATH	VPS37-1	physical	21442383
VP372_ARATH	AT2G36680	physical	21442383
VP221_ARATH	VPS22	physical	21442383
VP201_ARATH	VPS20.1	physical	21442383
VPS36_ARATH	AT5G04920	physical	21442383

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ELC_ARATH

Related Literatures of Post-Translational Modification