dbPTM

VATE_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VATE_DROME
UniProt AC	P54611
Protein Name	V-type proton ATPase subunit E
Gene Name	Vha26
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	226
Subcellular Localization
Protein Description	Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells..
Protein Sequence	MALSDADVQKQIKHMMAFIEQEANEKAEEIDAKAEEEFNIEKGRLVQQQRLKIMEYYEKKEKQVELQKKIQSSNMLNQARLKVLKVREDHVSSVLDDARKRLGEVTKNQSEYETVLTKLIVQGLFQIMEPKVILRCREVDVPLVRNVLPAAVEQYKAQINQNVELFIDEKDFLSADTCGGVELLALNGRIKVPNTLESRLDLISQQLVPEIRNALFGRNVNRKFTD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
10	Acetylation	LSDADVQKQIKHMMA CCHHHHHHHHHHHHH	54.56	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VATE_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VATE_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VATE_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VATH_DROME	VhaSFD	physical	14605208
VATG_DROME	Vha13	physical	14605208
TNG2_DROME	Tango2	physical	14605208
UBIQP_DROME	Ubi-p63E	physical	14605208
TCTP_DROME	Tctp	physical	14605208
UBCD1_DROME	eff	physical	14605208
EF1A1_DROME	Ef1alpha48D	physical	14605208
VATA2_DROME	Vha68-2	physical	22036573
VATD1_DROME	Vha36-1	physical	22036573
VATC_DROME	Vha44	physical	22036573
VATH_DROME	VhaSFD	physical	22036573
VATA1_DROME	Vha68-1	physical	22036573
COQ6_DROME	CG7277	physical	22036573

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VATE_DROME

Related Literatures of Post-Translational Modification