UBCD1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UBCD1_DROME
• UniProt AC: P25867
• Protein Name: Ubiquitin-conjugating enzyme E2-17 kDa
• Gene Name: eff
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 147
• Protein Description: Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Required for proper telomere behavior during cell divisions and possibly for ubiquitination of proteins involved in postmeiotic stages of spermatogenesis. Deletion mutations are lethal in homozygotes..
• Protein Sequence: MALKRINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAREWTRKYAM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Acetylation	MALKRINKELQDLGR CCHHHHHHHHHHCCC	58.38	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UBCD1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UBCD1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UBCD1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
NCAH_DROME	Nca	physical	14605208
SINA_DROME	sina	physical	9267026
TTKB_DROME	ttk	physical	9267026
TTKA_DROME	ttk	physical	9267026
CCNA_DROME	CycA	genetic	19906849
CCNA_DROME	CycA	genetic	10644410
DIAP1_DROME	th	physical	12021769

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.