NCAH_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NCAH_DROME
• UniProt AC: P42325
• Protein Name: Neurocalcin homolog
• Gene Name: Nca
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 190
• Protein Description: Inhibits the phosphorylation of rhodopsin in a calcium-dependent manner. Probably binds two or three calcium ions..
• Protein Sequence: MGKQNSKLKPEVLEDLKQNTEFTDAEIQEWYKGFLKDCPSGHLSVEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFLCALSVTSRGKLEQKLKWAFSMYDLDGNGYISRQEMLEIVTAIYKMVGSVMKMPEDESTPEKRTDKIFRQMDRNKDGKLSLEEFIEGAKSDPSIVRLLQCDPQSH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	N-myristoyl glycine	------MGKQNSKLK ------CCCCCCCCC	40.01	-
2	Myristoylation	------MGKQNSKLK ------CCCCCCCCC	40.01	8626592

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NCAH_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NCAH_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NCAH_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Myristoylation

"Drosophila neurocalcin, a fatty acylated, Ca2+-binding protein thatassociates with membranes and inhibits in vitro phosphorylation ofbovine rhodopsin.";
Faurobert E., Chen C.-K., Hurley J.B., Teng D.H.-F.;
J. Biol. Chem. 271:10256-10262(1996).
Cited for: FUNCTION, MASS SPECTROMETRY, AND MYRISTOYLATION AT GLY-2.
PubMed: 8626592