dbPTM

COQ6_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	COQ6_DROME
UniProt AC	Q9VMQ5
Protein Name	Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial {ECO:0000255\|HAMAP-Rule:MF_03193}
Gene Name	Coq6 {ECO:0000255\|HAMAP-Rule:MF_03193}
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	477
Subcellular Localization	Mitochondrion inner membrane Peripheral membrane protein Matrix side .
Protein Description	FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6..
Protein Sequence	MLGVLRIQGALASAGQARLLSVRLLASKSTTDMTTNRGESTQSTSTEHFDIIIGGGGLVGTTLAAALAKNSTLADKKVLLLEGAPEFRGFNPTGPYQNRVSAINHNSIELFKSIDAWKHIESARYKPVKQMQVWESNTDALIQFQHDNFASDVACIIENDLILDAVYALAKESPNVEILNKARIQCVRLPRDSNSNHSELQLEDGRNFSCDLLIGADGANSVVRKEMNVDVFSLNYDRMGLVATLELGEDACDNSVAWQRFLPNGPVALLPLTDRLSSLVWSTTNEQAKMLQALPPTEFVDALNEAFCRQYPRVELADKAVQALNSLFGHNGSQHQVQYPPRVCGVLDKSRATFPLGFLHASSYVCNGAALVGDAAHRVHPLAGQGVNLGFSDVRYLVESLAAGAYAGFKLGDKQHLIKYERKCLAKNVPIMLGVHGLHTLYATQFSPVVLLRSLGLQLTQNLPPVKNLFMRGAMGQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of COQ6_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of COQ6_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of COQ6_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of COQ6_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of COQ6_DROME

Related Literatures of Post-Translational Modification