VATB_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VATB_DROME
• UniProt AC: P31409
• Protein Name: V-type proton ATPase subunit B
• Gene Name: Vha55
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 490
• Protein Description: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells..
• Protein Sequence: MNAQQAQREHVLAVSRDFISQPRLTYKTVSGVNGPLVILDEVKFPKFAEIVQLRLADGTVRSGQVLEVSGSKAVVQVFEGTSGIDAKNTLCEFTGDILRTPVSEDMLGRVFNGSGKPIDKGPPILAEDFLDIQGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSAAGLPHNEIAAQICRQAGLVKLPGKSVLDDHTDNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRLALTAAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRQIYPPVNVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYACYAIGKDVQAMKAVVGEEALTPDDLLYLEFLTKFEKNFISQGNYENRTVFESLDIGWQLLRIFPKEMLKRIPASILAEFYPRDSRH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	REHVLAVSRDFISQP HHHHHHCCHHHHCCC	22.11	21082442
81	Phosphorylation	VVQVFEGTSGIDAKN EEEEEECCCCCCCCC	19.31	27794539
82	Phosphorylation	VQVFEGTSGIDAKNT EEEEECCCCCCCCCC	44.61	27794539
488	Phosphorylation	AEFYPRDSRH----- HHHCCCCCCC-----	33.27	21082442

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VATB_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VATB_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VATB_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VATE_DROME	Vha26	physical	22036573
VATA2_DROME	Vha68-2	physical	22036573
VATD1_DROME	Vha36-1	physical	22036573
VATC_DROME	Vha44	physical	22036573
COQ6_DROME	CG7277	physical	22036573
LST8_DROME	Lst8	physical	22036573
C6A13_DROME	Cyp6a13	physical	22036573
VATF1_DROME	Vha14-1	physical	22036573
VATH_DROME	VhaSFD	physical	22036573
NOTCH_DROME	N	genetic	20460366

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.