| UniProt ID | TTC23_HUMAN | |
|---|---|---|
| UniProt AC | Q5W5X9 | |
| Protein Name | Tetratricopeptide repeat protein 23 | |
| Gene Name | TTC23 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 447 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MQESQETHISNHLDEVVAAVSITHRKKFQNKLLQTALFQPPREKLHLCEEKAKSYSNSHEYKQAVHELVRCVALTRICYGDSHWKLAEAHVNLAQGYLQLKGLSLQAKQHAEKARQILANSIVPPYSENTDVFKFSIELFHTMGRALLSLQKFKEAAENLTKAERLSKELLQCGRIIKEEWIEIEARIRLSFAQVYQGQKKSKEALSHYQAALEYVEISKGETSRECVPILRELAGVEQALGLHDVSINHFLQAHLIILSRSPSQVEAADSAHIVAHAAVASGRHEHHDVAEQYFQESMAHLKDSEGMGRTKFLSIQDEFCHFLQMTGQKERATSILRESLEAKVEAFGDFSPEVAETYRLLGGADLAQGNHSGARKKLKKCLQIQTLLYGPQDKRTLATQQAMGMLSTAPKVASKPRQASKAKVAFCTSIPQDTLLGKARPGTTAD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 54 | Phosphorylation | LCEEKAKSYSNSHEY HCHHHHHHCCCCHHH | 38.36 | 30631047 | |
| 149 | Phosphorylation | TMGRALLSLQKFKEA HHHHHHHHHHHHHHH | 29.60 | 24719451 | |
| 161 | Phosphorylation | KEAAENLTKAERLSK HHHHHHHHHHHHHHH | 39.53 | 22817900 | |
| 167 | Phosphorylation | LTKAERLSKELLQCG HHHHHHHHHHHHHHC | 30.24 | - | |
| 334 | O-linked_Glycosylation | TGQKERATSILRESL HCCHHHHHHHHHHHH | 23.63 | 31492838 | |
| 334 | Phosphorylation | TGQKERATSILRESL HCCHHHHHHHHHHHH | 23.63 | 28348404 | |
| 335 | O-linked_Glycosylation | GQKERATSILRESLE CCHHHHHHHHHHHHH | 20.74 | 31492838 | |
| 335 | Phosphorylation | GQKERATSILRESLE CCHHHHHHHHHHHHH | 20.74 | 24719451 | |
| 373 | Phosphorylation | DLAQGNHSGARKKLK CCCCCCCHHHHHHHH | 37.84 | 28555341 | |
| 400 | Phosphorylation | QDKRTLATQQAMGML CCHHHHHHHHHHHHH | 25.07 | 27282143 | |
| 408 | Phosphorylation | QQAMGMLSTAPKVAS HHHHHHHHCCHHHCC | 17.40 | 28842319 | |
| 409 | Phosphorylation | QAMGMLSTAPKVASK HHHHHHHCCHHHCCC | 42.91 | 27282143 | |
| 415 | Phosphorylation | STAPKVASKPRQASK HCCHHHCCCCCHHCC | 46.29 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TTC23_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TTC23_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TTC23_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A4_HUMAN | APP | physical | 21832049 | |
| LZTS2_HUMAN | LZTS2 | physical | 25416956 | |
| PNMA5_HUMAN | PNMA5 | physical | 25416956 | |
| CNTRB_HUMAN | CNTROB | physical | 25416956 | |
| ADIP_HUMAN | SSX2IP | physical | 25416956 | |
| K1C40_HUMAN | KRT40 | physical | 25416956 | |
| KR103_HUMAN | KRTAP10-3 | physical | 25416956 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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