| UniProt ID | TRI49_HUMAN | |
|---|---|---|
| UniProt AC | P0CI25 | |
| Protein Name | Tripartite motif-containing protein 49 | |
| Gene Name | TRIM49 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 452 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANNDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKIDGKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MNSGILQVFQ -----CCCCHHHHHC | 26.38 | - | |
| 75 | Phosphorylation | IHLKKMASLARKVSL HHHHHHHHHHHHHHH | 21.04 | - | |
| 150 | Acetylation | KMQSLWEKACENHRN HHHHHHHHHHHHCCC | 46.91 | 7976177 | |
| 202 | "N6,N6-dimethyllysine" | KHNLEMLKKKGKEIF HHCHHHHHHHHHHHH | 51.64 | - | |
| 202 | Methylation | KHNLEMLKKKGKEIF HHCHHHHHHHHHHHH | 51.64 | - | |
| 255 | Phosphorylation | FGDILHRSESVLLHM HHHHHHHCCEEEECC | 24.39 | - | |
| 257 | Phosphorylation | DILHRSESVLLHMPQ HHHHHCCEEEECCCC | 21.22 | - | |
| 276 | Phosphorylation | ELSAGPITGLRDRLN CCCCCCCCCHHHHHH | 33.04 | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TRI49_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TRI49_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TRI49_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| BLM_HUMAN | BLM | physical | 23708797 | |
| CUL1_HUMAN | CUL1 | physical | 26186194 | |
| SKP2_HUMAN | SKP2 | physical | 26186194 | |
| CKS1_HUMAN | CKS1B | physical | 26186194 | |
| CKS1_HUMAN | CKS1B | physical | 28514442 | |
| SKP2_HUMAN | SKP2 | physical | 28514442 | |
| MINY3_HUMAN | FAM188A | physical | 28514442 | |
| LEG3_HUMAN | LGALS3 | physical | 27693506 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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