THA10_HUMAN - dbPTM
THA10_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID THA10_HUMAN
UniProt AC Q9P2Z0
Protein Name THAP domain-containing protein 10
Gene Name THAP10
Organism Homo sapiens (Human).
Sequence Length 257
Subcellular Localization
Protein Description
Protein Sequence MPARCVAAHCGNTTKSGKSLFRFPKDRAVRLLWDRFVRGCRADWYGGNDRSVICSDHFAPACFDVSSVIQKNLRFSQRLRLVAGAVPTLHRVPAPAPKRGEEGDQAGRLDTRGELQAARHSEAAPGPVSCTRPRAGKQAAASQITCENELVQTQPHADNPSNTVTSVPTHCEEGPVHKSTQISLKRPRHRSVGIQAKVKAFGKRLCNATTQTEELWSRTSSLFDIYSSDSETDTDWDIKSEQSDLSYMAVQVKEETC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationHCGNTTKSGKSLFRF
CCCCCCCCCCCCCCC
49.7327251275
19PhosphorylationNTTKSGKSLFRFPKD
CCCCCCCCCCCCCHH
35.9424719451
76PhosphorylationIQKNLRFSQRLRLVA
HHHHCCHHHHHHHHH
14.14-
88PhosphorylationLVAGAVPTLHRVPAP
HHHCCCCCCCCCCCC
28.70-
112DimethylationQAGRLDTRGELQAAR
CCCCCCCHHHHHHHH
35.93-
112MethylationQAGRLDTRGELQAAR
CCCCCCCHHHHHHHH
35.9324380127
183PhosphorylationVHKSTQISLKRPRHR
CCCCCEEEECCCCCC
20.30-
197AcetylationRSVGIQAKVKAFGKR
CCCHHHHHHHHHHHH
28.0830592935
199AcetylationVGIQAKVKAFGKRLC
CHHHHHHHHHHHHHH
36.9730592939
203AcetylationAKVKAFGKRLCNATT
HHHHHHHHHHHCCCC
35.4330592943
227PhosphorylationSSLFDIYSSDSETDT
HHHHHCCCCCCCCCC
28.1822817900
228PhosphorylationSLFDIYSSDSETDTD
HHHHCCCCCCCCCCC
28.3422817900
230PhosphorylationFDIYSSDSETDTDWD
HHCCCCCCCCCCCCC
44.3222817900
232PhosphorylationIYSSDSETDTDWDIK
CCCCCCCCCCCCCCC
48.4217081983
234PhosphorylationSSDSETDTDWDIKSE
CCCCCCCCCCCCCCC
46.5417081983

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of THA10_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of THA10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of THA10_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
KR412_HUMANKRTAP4-12physical
16189514
DYL2_HUMANDYNLL2physical
16189514
LZTS2_HUMANLZTS2physical
25416956
KR109_HUMANKRTAP10-9physical
25416956
KR108_HUMANKRTAP10-8physical
25416956
KR103_HUMANKRTAP10-3physical
25416956
TP53B_HUMANTP53BP1physical
26186194
TP53B_HUMANTP53BP1physical
28514442

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of THA10_HUMAN

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Related Literatures of Post-Translational Modification

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