T10IP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T10IP_HUMAN
• UniProt AC: Q3SY00
• Protein Name: Testis-specific protein 10-interacting protein
• Gene Name: TSGA10IP
• Organism: Homo sapiens (Human).
• Sequence Length: 556
• Protein Sequence: MGQDTDMLNTYQQLVRTPSVRPGQDVRLQAPGTRTGLLKLLSTVSQDKQGCLGSGDGVPNQDLQQRSQSSRQTAKKDRKPRGQSKKGQGSEESEDHFPLLPRKPSFPFQWAWESIATDVRAVLQPSSPTPGHQALPMPSSFSQRQSRRKSTANLPEAHGCCWKTEAQNLKARQQLGAWGGVSIPTGKGELGSEPPSGLQLPGRRPGSGSASDKQVQLQSLGAEEAERGLSSGVLPQRPRRGSISEEEQFSEATEEAEEGEHRTPCRRRAGCQRKGQISGEEASDEGEVQGQSQGSSPSFNNLRRRQWRKTRAKELQGPWDLEKLHRQLQRDLDCGPQKLPWKTLRAAFQASKRNGKAYASGYDETFVSANLPNRTFHKRQEATRSLLQAWERQRQEERQQAELRRARTQHVQRQVAHCLAAYAPRGSRGPGAAQRKLEELRRQERQRFAEYQAELQGIQHRVQARPFLFQQAMQANARLTVTRRFSQVLSALGLDEEQLLSEAGKVDREGTPRKPRSHRSMGVRMEHSPQRPPRTEPTGSQPDRHYNPSLDPECSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MGQDTDMLNTYQ ---CCCCHHHHHHHH	18.54	24719451
10	Phosphorylation	QDTDMLNTYQQLVRT CCHHHHHHHHHHHCC	20.81	24043423
11	Phosphorylation	DTDMLNTYQQLVRTP CHHHHHHHHHHHCCC	8.00	24043423
17	Phosphorylation	TYQQLVRTPSVRPGQ HHHHHHCCCCCCCCC	16.67	24043423
19	Phosphorylation	QQLVRTPSVRPGQDV HHHHCCCCCCCCCCE	30.10	24043423
90	Phosphorylation	QSKKGQGSEESEDHF CCCCCCCCCCCCCCC	30.24	26434776
93	Phosphorylation	KGQGSEESEDHFPLL CCCCCCCCCCCCCCC	44.25	26434776
105	Phosphorylation	PLLPRKPSFPFQWAW CCCCCCCCCCCCCHH	48.89	22210691
117	Phosphorylation	WAWESIATDVRAVLQ CHHHHHHHHHHHHHC	33.10	22210691
192	Phosphorylation	TGKGELGSEPPSGLQ CCCCCCCCCCCCCCC	60.60	-
196	Phosphorylation	ELGSEPPSGLQLPGR CCCCCCCCCCCCCCC	63.95	-
219	Phosphorylation	DKQVQLQSLGAEEAE HHHHHHHHHCHHHHH	37.05	29978859
511	Phosphorylation	GKVDREGTPRKPRSH CCCCCCCCCCCCCCC	18.37	-
517	Phosphorylation	GTPRKPRSHRSMGVR CCCCCCCCCCCCCCC	31.60	-
520	Phosphorylation	RKPRSHRSMGVRMEH CCCCCCCCCCCCCCC	20.14	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T10IP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T10IP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T10IP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CCD57_HUMAN	CCDC57	physical	25416956
BRCA1_HUMAN	BRCA1	physical	25184681
NAA16_HUMAN	NAA16	physical	26186194
CUL2_HUMAN	CUL2	physical	26186194
ZY11B_HUMAN	ZYG11B	physical	26186194
YBEY_HUMAN	YBEY	physical	26186194
DCAF5_HUMAN	DCAF5	physical	26186194
NAA10_HUMAN	NAA10	physical	26186194
NAA50_HUMAN	NAA50	physical	26186194
HYPK_HUMAN	HYPK	physical	26186194
CYTS_HUMAN	CST4	physical	26186194
NAA16_HUMAN	NAA16	physical	28514442
ZY11B_HUMAN	ZYG11B	physical	28514442
NAA50_HUMAN	NAA50	physical	28514442
HYPK_HUMAN	HYPK	physical	28514442
CUL2_HUMAN	CUL2	physical	28514442
DCAF5_HUMAN	DCAF5	physical	28514442
NAA10_HUMAN	NAA10	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.