| UniProt ID | SYNP2_HUMAN | |
|---|---|---|
| UniProt AC | Q9UMS6 | |
| Protein Name | Synaptopodin-2 | |
| Gene Name | SYNPO2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 1093 | |
| Subcellular Localization | Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell junction, focal adhesion . Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. In undifferentiated my | |
| Protein Description | Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner. [PubMed: 24005909] | |
| Protein Sequence | MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEEGDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALDVMKHQPYQLNASLFTFQPPDAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQVWKPSVVEE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MGTGDFICIS -----CCCCCEEEEE | 45.49 | 23836654 | |
| 10 | Phosphorylation | TGDFICISMTGGAPW CCCEEEEECCCCCCC | 13.09 | 23532336 | |
| 75 | Phosphorylation | EVIKLMESITDSLQM HHHHHHHHHHHHHHH | 19.47 | 30631047 | |
| 77 | Phosphorylation | IKLMESITDSLQMLI HHHHHHHHHHHHHHH | 28.90 | 30631047 | |
| 79 | Phosphorylation | LMESITDSLQMLIKR HHHHHHHHHHHHHHC | 16.32 | 30631047 | |
| 88 | Phosphorylation | QMLIKRPSSGISEAL HHHHHCCCCCHHHHH | 45.27 | 28348404 | |
| 89 | Phosphorylation | MLIKRPSSGISEALI HHHHCCCCCHHHHHH | 42.71 | 26657352 | |
| 92 | Phosphorylation | KRPSSGISEALISEN HCCCCCHHHHHHCCC | 21.97 | 23312004 | |
| 97 | Phosphorylation | GISEALISENENKNL CHHHHHHCCCCCCCH | 34.91 | 23312004 | |
| 112 | Phosphorylation | EHLTHGGYVESTTLQ HHHCCCCEEEEEEEE | 12.97 | - | |
| 148 | Phosphorylation | PLAENQRSGPDCAGS CCCCCCCCCCCCCCC | 44.93 | 27499020 | |
| 155 | Phosphorylation | SGPDCAGSLKEETGP CCCCCCCCCCCCCCC | 20.10 | 26657352 | |
| 202 | Phosphorylation | PVVELQLSLSQERHK CEEEEEEEECHHHHC | 17.02 | 27251275 | |
| 204 | Phosphorylation | VELQLSLSQERHKGA EEEEEEECHHHHCCC | 26.98 | 24275569 | |
| 212 | Phosphorylation | QERHKGASGPLVALP HHHHCCCCCCEEECC | 50.00 | 27251275 | |
| 224 | Phosphorylation | ALPGAEKSKSPDPDP ECCCCCCCCCCCCCC | 29.85 | 24972180 | |
| 226 | Phosphorylation | PGAEKSKSPDPDPNL CCCCCCCCCCCCCCC | 41.44 | 23911959 | |
| 234 | Phosphorylation | PDPDPNLSHDRIVHI CCCCCCCCCCCEEEE | 29.95 | 26657352 | |
| 243 | Phosphorylation | DRIVHINSIPTNEKA CCEEEEECCCCCCCC | 29.37 | 26657352 | |
| 256 | Phosphorylation | KADPFLRSSKIIQIS CCCHHHHCCCEEEEC | 37.82 | 24719451 | |
| 257 | Phosphorylation | ADPFLRSSKIIQISS CCHHHHCCCEEEECC | 22.80 | 24719451 | |
| 263 | Phosphorylation | SSKIIQISSGRELRV CCCEEEECCCCEEEE | 15.46 | 24670416 | |
| 264 | Phosphorylation | SKIIQISSGRELRVI CCEEEECCCCEEEEE | 43.42 | 28857561 | |
| 274 | Phosphorylation | ELRVIQESEAGDAGL EEEEEECCCCCCCCC | 19.17 | 26657352 | |
| 291 | Phosphorylation | VEVILDCSDRQKTEG EEEEEECCHHHCCCC | 35.18 | 27499020 | |
| 310 | Phosphorylation | AGKECVDSPVEGGQS CCCCCCCCCCCCCCC | 15.50 | 26657352 | |
| 317 | Phosphorylation | SPVEGGQSEAPPSLV CCCCCCCCCCCCCCE | 38.71 | 28348404 | |
| 322 | Phosphorylation | GQSEAPPSLVSFAVS CCCCCCCCCEEEEEE | 40.10 | 26657352 | |
| 325 | Phosphorylation | EAPPSLVSFAVSSEG CCCCCCEEEEEECCC | 16.87 | 30177828 | |
| 329 | Phosphorylation | SLVSFAVSSEGTEQG CCEEEEEECCCCCCC | 21.17 | 26657352 | |
| 330 | Phosphorylation | LVSFAVSSEGTEQGE CEEEEEECCCCCCCC | 33.18 | 26657352 | |
| 333 | Phosphorylation | FAVSSEGTEQGEDPR EEEECCCCCCCCCCC | 22.53 | 28348404 | |
| 341 | Phosphorylation | EQGEDPRSEKDHSRP CCCCCCCCCCCCCCC | 55.15 | 30177828 | |
| 346 | Phosphorylation | PRSEKDHSRPHKHRA CCCCCCCCCCCHHHH | 58.61 | 23403867 | |
| 361 | Phosphorylation | RHARLRRSESLSEKQ HHHHHHHCCCCCHHH | 25.71 | 17494752 | |
| 363 | Phosphorylation | ARLRRSESLSEKQVK HHHHHCCCCCHHHHH | 38.14 | 24972180 | |
| 365 | Phosphorylation | LRRSESLSEKQVKEA HHHCCCCCHHHHHHH | 52.61 | 26699800 | |
| 374 | Phosphorylation | KQVKEAKSKCKSIAL HHHHHHHHHHHHHHH | 50.78 | 17494752 | |
| 378 | Phosphorylation | EAKSKCKSIALLLTD HHHHHHHHHHHHHCC | 23.67 | 27251275 | |
| 398 | Ubiquitination | SKGVLMFKKRRRRAR CCCEEEEEHHHHHCH | 31.25 | - | |
| 407 | Phosphorylation | RRRRARKYTLVSYGT HHHHCHHEEEEEECC | 10.35 | 23312004 | |
| 408 | Phosphorylation | RRRARKYTLVSYGTG HHHCHHEEEEEECCC | 24.58 | 28857561 | |
| 411 | Phosphorylation | ARKYTLVSYGTGELE CHHEEEEEECCCCCC | 22.43 | 28857561 | |
| 412 | Phosphorylation | RKYTLVSYGTGELER HHEEEEEECCCCCCC | 15.95 | 22210691 | |
| 441 | Phosphorylation | EVAFLGASESEVDEE EEEEECCCHHHCCHH | 39.60 | 24275569 | |
| 443 | Phosphorylation | AFLGASESEVDEELL EEECCCHHHCCHHHH | 40.19 | 24275569 | |
| 506 | Phosphorylation | RERMDQITAQKEEDK HHHHHHHHHHHHHHC | 19.87 | 19651622 | |
| 517 | Phosphorylation | EEDKVGGTPSREQDA HHHCCCCCCCHHHHH | 16.50 | 23312004 | |
| 519 | Phosphorylation | DKVGGTPSREQDAAQ HCCCCCCCHHHHHHH | 48.57 | 26657352 | |
| 543 | Phosphorylation | YQRKEEESVRTQSSV HHHHHHHHHHCCHHH | 21.85 | 26437602 | |
| 548 | Phosphorylation | EESVRTQSSVSKSYI HHHHHCCHHHCHHHE | 31.90 | - | |
| 549 | Phosphorylation | ESVRTQSSVSKSYIE HHHHCCHHHCHHHEE | 22.16 | - | |
| 551 | Phosphorylation | VRTQSSVSKSYIEVS HHCCHHHCHHHEEEE | 20.17 | - | |
| 573 | Phosphorylation | QQNGFSGTSETANIQ CCCCCCCCCCCCCCE | 23.38 | 26657352 | |
| 588 | Phosphorylation | RMVPMNRTAKPFPGS EEEECCCCCCCCCCC | 33.75 | 26437602 | |
| 595 | Phosphorylation | TAKPFPGSVNQPATP CCCCCCCCCCCCCCC | 20.38 | 26657352 | |
| 601 | Phosphorylation | GSVNQPATPFSPTRN CCCCCCCCCCCCCCC | 31.39 | 24670416 | |
| 604 | Phosphorylation | NQPATPFSPTRNMTS CCCCCCCCCCCCCCC | 26.94 | 24972180 | |
| 606 | Phosphorylation | PATPFSPTRNMTSPI CCCCCCCCCCCCCCC | 33.21 | 24972180 | |
| 610 | Phosphorylation | FSPTRNMTSPIADFP CCCCCCCCCCCCCCC | 34.59 | 25072903 | |
| 611 | Phosphorylation | SPTRNMTSPIADFPA CCCCCCCCCCCCCCC | 11.98 | 25072903 | |
| 622 | Phosphorylation | DFPAPPPYSAVTPPP CCCCCCCCCCCCCCC | 18.29 | 26657352 | |
| 623 | Phosphorylation | FPAPPPYSAVTPPPD CCCCCCCCCCCCCCC | 23.26 | 25072903 | |
| 626 | Phosphorylation | PPPYSAVTPPPDAFS CCCCCCCCCCCCHHH | 29.78 | 25072903 | |
| 633 | Phosphorylation | TPPPDAFSRGVSSPI CCCCCHHHCCCCCCC | 29.82 | 29691806 | |
| 637 | Phosphorylation | DAFSRGVSSPIAGPA CHHHCCCCCCCCCCC | 32.97 | 26657352 | |
| 638 | Phosphorylation | AFSRGVSSPIAGPAQ HHHCCCCCCCCCCCC | 20.23 | 26657352 | |
| 656 | Phosphorylation | WPQPAPWSQPAFYDS CCCCCCCCCCCCCCC | 25.81 | 22673903 | |
| 661 | Phosphorylation | PWSQPAFYDSSERIA CCCCCCCCCCHHHHH | 19.61 | 22673903 | |
| 663 | Phosphorylation | SQPAFYDSSERIASR CCCCCCCCHHHHHCC | 23.79 | 22673903 | |
| 664 | Phosphorylation | QPAFYDSSERIASRD CCCCCCCHHHHHCCC | 28.17 | 22673903 | |
| 669 | Phosphorylation | DSSERIASRDERISV CCHHHHHCCCCCCCC | 37.58 | 26437602 | |
| 675 | Phosphorylation | ASRDERISVPAKRTG HCCCCCCCCCHHHHC | 28.41 | 26437602 | |
| 688 | Ubiquitination | TGILQEAKRRSTTKP HCHHHHHHHHCCCCC | 47.82 | - | |
| 688 (in isoform 2) | Ubiquitination | - | 47.82 | - | |
| 691 | Phosphorylation | LQEAKRRSTTKPMFT HHHHHHHCCCCCCEE | 44.45 | 26657352 | |
| 692 | Phosphorylation | QEAKRRSTTKPMFTF HHHHHHCCCCCCEEC | 36.71 | 28857561 | |
| 693 | Phosphorylation | EAKRRSTTKPMFTFK HHHHHCCCCCCEECC | 34.10 | 26657352 | |
| 705 | Phosphorylation | TFKEPKVSPNPELLS ECCCCCCCCCHHHHH | 25.70 | 26657352 | |
| 712 | Phosphorylation | SPNPELLSLLQNSEG CCCHHHHHHHHCCCC | 39.39 | 26657352 | |
| 717 | Phosphorylation | LLSLLQNSEGKRGTG HHHHHHCCCCCCCCC | 34.46 | 27732954 | |
| 720 | Acetylation | LLQNSEGKRGTGAGG HHHCCCCCCCCCCCC | 43.53 | 19863737 | |
| 723 | Phosphorylation | NSEGKRGTGAGGDSG CCCCCCCCCCCCCCC | 28.08 | 26657352 | |
| 729 | Phosphorylation | GTGAGGDSGPEEDYL CCCCCCCCCCHHHHH | 60.57 | 25849741 | |
| 735 | Phosphorylation | DSGPEEDYLSLGAEA CCCCHHHHHHHHHHH | 11.06 | 26657352 | |
| 737 | Phosphorylation | GPEEDYLSLGAEACN CCHHHHHHHHHHHHH | 20.66 | 26657352 | |
| 748 | Phosphorylation | EACNFMQSSSAKQKT HHHHHHHCCCCCCCC | 17.93 | 28258704 | |
| 755 | Phosphorylation | SSSAKQKTPPPVAPK CCCCCCCCCCCCCCC | 38.24 | 26657352 | |
| 766 | Acetylation | VAPKPAVKSSSSQPV CCCCCCCCCCCCCCC | 46.88 | 30586203 | |
| 767 | Phosphorylation | APKPAVKSSSSQPVT CCCCCCCCCCCCCCC | 28.93 | 26657352 | |
| 768 | Phosphorylation | PKPAVKSSSSQPVTP CCCCCCCCCCCCCCC | 28.43 | 22199227 | |
| 769 | Phosphorylation | KPAVKSSSSQPVTPV CCCCCCCCCCCCCCC | 39.83 | 22199227 | |
| 770 | Phosphorylation | PAVKSSSSQPVTPVS CCCCCCCCCCCCCCC | 40.21 | 26657352 | |
| 774 | Phosphorylation | SSSSQPVTPVSPVWS CCCCCCCCCCCCCCC | 25.34 | 26657352 | |
| 777 | Phosphorylation | SQPVTPVSPVWSPGV CCCCCCCCCCCCCCC | 18.23 | 19276368 | |
| 781 | Phosphorylation | TPVSPVWSPGVAPTQ CCCCCCCCCCCCCCC | 16.41 | 25072903 | |
| 787 | Phosphorylation | WSPGVAPTQPPAFPT CCCCCCCCCCCCCCC | 43.93 | 26657352 | |
| 794 | Phosphorylation | TQPPAFPTSNPSKGT CCCCCCCCCCCCCCC | 34.38 | 27251275 | |
| 795 | Phosphorylation | QPPAFPTSNPSKGTV CCCCCCCCCCCCCCE | 47.16 | 27251275 | |
| 798 | Phosphorylation | AFPTSNPSKGTVVSS CCCCCCCCCCCEEEE | 48.22 | 24275569 | |
| 801 | Phosphorylation | TSNPSKGTVVSSIKI CCCCCCCCEEEEEEE | 22.82 | - | |
| 804 | Phosphorylation | PSKGTVVSSIKIAQP CCCCCEEEEEEECCC | 23.24 | 23312004 | |
| 805 | Phosphorylation | SKGTVVSSIKIAQPS CCCCEEEEEEECCCC | 19.11 | 28857561 | |
| 812 | Phosphorylation | SIKIAQPSYPPARPA EEEECCCCCCCCCCC | 37.89 | 23312004 | |
| 813 | Phosphorylation | IKIAQPSYPPARPAS EEECCCCCCCCCCCC | 21.66 | 23312004 | |
| 820 | Phosphorylation | YPPARPASTLNVAGP CCCCCCCCEECCCCC | 35.79 | 26657352 | |
| 821 | Phosphorylation | PPARPASTLNVAGPF CCCCCCCEECCCCCC | 25.18 | 28857561 | |
| 840 | Phosphorylation | AAVASQNYTPKPTVS CEEECCCCCCCCCCC | 19.44 | 28857561 | |
| 841 | Phosphorylation | AVASQNYTPKPTVST EEECCCCCCCCCCCC | 32.17 | 28857561 | |
| 845 | Phosphorylation | QNYTPKPTVSTPTVN CCCCCCCCCCCCCCC | 32.96 | 28857561 | |
| 847 | Phosphorylation | YTPKPTVSTPTVNAV CCCCCCCCCCCCCCC | 31.02 | 28348404 | |
| 848 | Phosphorylation | TPKPTVSTPTVNAVQ CCCCCCCCCCCCCCC | 20.74 | 28857561 | |
| 850 | Phosphorylation | KPTVSTPTVNAVQPG CCCCCCCCCCCCCCC | 26.87 | 28857561 | |
| 881 | Phosphorylation | QLFAKRQSRMEKYVV HHHHHHHHHHHEEEE | 37.31 | 26657352 | |
| 886 | Phosphorylation | RQSRMEKYVVDSDTV HHHHHHEEEECHHHH | 7.75 | 29514088 | |
| 890 | Phosphorylation | MEKYVVDSDTVQAHA HHEEEECHHHHHHHH | 24.46 | 29514088 | |
| 892 | Phosphorylation | KYVVDSDTVQAHAAR EEEECHHHHHHHHHH | 20.61 | 29514088 | |
| 902 | Phosphorylation | AHAARAQSPTPSLPA HHHHHCCCCCCCCCC | 29.74 | 30278072 | |
| 904 | Phosphorylation | AARAQSPTPSLPASW HHHCCCCCCCCCCCC | 30.65 | 26329039 | |
| 906 | Phosphorylation | RAQSPTPSLPASWKY HCCCCCCCCCCCCCC | 49.84 | 26503892 | |
| 910 | Phosphorylation | PTPSLPASWKYSSNV CCCCCCCCCCCCCCC | 23.35 | 30242111 | |
| 913 | Phosphorylation | SLPASWKYSSNVRAP CCCCCCCCCCCCCCC | 15.86 | 22673903 | |
| 914 | Phosphorylation | LPASWKYSSNVRAPP CCCCCCCCCCCCCCC | 16.23 | 22673903 | |
| 915 | Phosphorylation | PASWKYSSNVRAPPP CCCCCCCCCCCCCCC | 35.93 | 22673903 | |
| 925 | Phosphorylation | RAPPPVAYNPIHSPS CCCCCCCCCCCCCCC | 23.00 | 27732954 | |
| 930 | Phosphorylation | VAYNPIHSPSYPLAA CCCCCCCCCCCCHHH | 19.09 | 24972180 | |
| 932 | Phosphorylation | YNPIHSPSYPLAALK CCCCCCCCCCHHHHH | 42.26 | 26699800 | |
| 933 | Phosphorylation | NPIHSPSYPLAALKS CCCCCCCCCHHHHHC | 12.97 | 28857561 | |
| 940 | Phosphorylation | YPLAALKSQPSAAQP CCHHHHHCCCCCCCC | 48.45 | 26437602 | |
| 943 | Phosphorylation | AALKSQPSAAQPSKM HHHHCCCCCCCCHHC | 28.71 | 26437602 | |
| 993 | Phosphorylation | DGLPQKSSVKVNSAL CCCCCCCCCCHHHHH | 32.75 | 26437602 | |
| 998 | Phosphorylation | KSSVKVNSALAMKQA CCCCCHHHHHHHHHC | 27.87 | 28857561 | |
| 1015 | Phosphorylation | PRPVNAASPTNVQAS CCCCCCCCCCCCCCC | 29.82 | 27251275 | |
| 1017 | Phosphorylation | PVNAASPTNVQASSV CCCCCCCCCCCCCCC | 45.59 | 27251275 | |
| 1026 | Phosphorylation | VQASSVYSVPAYTSP CCCCCCEECCCCCCC | 21.33 | 27251275 | |
| 1030 | Phosphorylation | SVYSVPAYTSPPSFF CCEECCCCCCCCCHH | 11.15 | 27251275 | |
| 1031 | Phosphorylation | VYSVPAYTSPPSFFA CEECCCCCCCCCHHH | 36.54 | 27251275 | |
| 1032 | Phosphorylation | YSVPAYTSPPSFFAE EECCCCCCCCCHHHH | 23.33 | 27251275 | |
| 1035 | Phosphorylation | PAYTSPPSFFAEASS CCCCCCCCHHHHCCC | 36.06 | 26657352 | |
| 1041 | Phosphorylation | PSFFAEASSPVSASP CCHHHHCCCCCCCCC | 27.04 | 26657352 | |
| 1042 | Phosphorylation | SFFAEASSPVSASPV CHHHHCCCCCCCCCC | 36.05 | 26657352 | |
| 1045 | Phosphorylation | AEASSPVSASPVPVG HHCCCCCCCCCCCCC | 26.81 | 26657352 | |
| 1047 | Phosphorylation | ASSPVSASPVPVGIP CCCCCCCCCCCCCCC | 20.94 | 26657352 | |
| 1048 (in isoform 4) | Phosphorylation | - | 33.86 | 26657352 | |
| 1051 (in isoform 4) | Phosphorylation | - | 12.66 | 30177828 | |
| 1055 | Phosphorylation | PVPVGIPTSPKQESA CCCCCCCCCCCCCCC | 56.60 | 26657352 | |
| 1055 (in isoform 4) | Phosphorylation | - | 56.60 | 27251275 | |
| 1056 | Phosphorylation | VPVGIPTSPKQESAS CCCCCCCCCCCCCCC | 25.42 | 26657352 | |
| 1058 (in isoform 4) | Phosphorylation | - | 67.47 | 29691806 | |
| 1060 (in isoform 4) | Phosphorylation | - | 55.16 | 29691806 | |
| 1061 | Phosphorylation | PTSPKQESASSSYFV CCCCCCCCCCCCCEE | 30.84 | 26657352 | |
| 1063 | Phosphorylation | SPKQESASSSYFVAP CCCCCCCCCCCEECC | 29.15 | 26657352 | |
| 1064 | Phosphorylation | PKQESASSSYFVAPR CCCCCCCCCCEECCC | 28.86 | 26657352 | |
| 1065 | Phosphorylation | KQESASSSYFVAPRP CCCCCCCCCEECCCC | 21.79 | 23312004 | |
| 1066 | Phosphorylation | QESASSSYFVAPRPK CCCCCCCCEECCCCC | 12.20 | 23312004 | |
| 1071 (in isoform 4) | Phosphorylation | - | 36.98 | 27251275 | |
| 1072 (in isoform 4) | Phosphorylation | - | 40.77 | 27251275 | |
| 1073 (in isoform 4) | Phosphorylation | - | 53.91 | 27251275 | |
| 1079 | Phosphorylation | PKFSAKKSGVTIQVW CCCCCCCCCCEEEEE | 37.48 | 28857561 | |
| 1079 (in isoform 2) | Phosphorylation | - | 37.48 | 26657352 | |
| 1080 (in isoform 4) | Phosphorylation | - | 29.48 | - | |
| 1082 | Phosphorylation | SAKKSGVTIQVWKPS CCCCCCCEEEEECCC | 14.82 | 26657352 | |
| 1082 (in isoform 2) | Phosphorylation | - | 14.82 | 30177828 | |
| 1085 (in isoform 4) | Phosphorylation | - | 6.66 | - | |
| 1086 (in isoform 2) | Phosphorylation | - | 7.17 | 27251275 | |
| 1089 | Phosphorylation | TIQVWKPSVVEE--- EEEEECCCCCCC--- | 34.76 | 26437602 | |
| 1089 (in isoform 2) | Phosphorylation | - | 34.76 | 29691806 | |
| 1091 (in isoform 2) | Phosphorylation | - | 8.85 | 29691806 | |
| 1102 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1103 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1104 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1107 (in isoform 4) | Phosphorylation | - | 26657352 | ||
| 1111 (in isoform 2) | Phosphorylation | - | - | ||
| 1116 (in isoform 2) | Phosphorylation | - | - | ||
| 1124 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1138 (in isoform 2) | Phosphorylation | - | 26657352 | ||
| 1150 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1151 (in isoform 4) | Phosphorylation | - | - | ||
| 1155 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1168 (in isoform 4) | Phosphorylation | - | - | ||
| 1177 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1178 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1179 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1180 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1181 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1182 (in isoform 2) | Phosphorylation | - | - | ||
| 1182 (in isoform 4) | Phosphorylation | - | 27251275 | ||
| 1191 (in isoform 4) | Phosphorylation | - | - | ||
| 1195 (in isoform 4) | Phosphorylation | - | 26657352 | ||
| 1199 (in isoform 2) | Phosphorylation | - | - | ||
| 1199 (in isoform 4) | Phosphorylation | - | 26657352 | ||
| 1208 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1208 (in isoform 4) | Phosphorylation | - | 26657352 | ||
| 1209 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1210 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1211 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1213 (in isoform 2) | Phosphorylation | - | 27251275 | ||
| 1222 (in isoform 2) | Phosphorylation | - | - | ||
| 1226 (in isoform 2) | Phosphorylation | - | 26657352 | ||
| 1230 (in isoform 2) | Phosphorylation | - | 26657352 | ||
| 1239 (in isoform 2) | Phosphorylation | - | 26657352 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SYNP2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SYNP2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SYNP2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| IPO13_HUMAN | IPO13 | physical | 17828378 | |
| BAG3_HUMAN | BAG3 | physical | 23434281 | |
| HSP7C_HUMAN | HSPA8 | physical | 23434281 | |
| SQSTM_HUMAN | SQSTM1 | physical | 23434281 | |
| FLNA_HUMAN | FLNA | physical | 23434281 | |
| VPS18_HUMAN | VPS18 | physical | 23434281 | |
| A16L1_HUMAN | ATG16L1 | physical | 23434281 | |
| MLP3A_HUMAN | MAP1LC3A | physical | 23434281 | |
| STX7_HUMAN | STX7 | physical | 23434281 | |
| ACTN2_HUMAN | ACTN2 | physical | 20554076 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "Automated phosphoproteome analysis for cultured cancer cells by two-dimensional nanoLC-MS using a calcined titania/C18 biphasic column."; Imami K., Sugiyama N., Kyono Y., Tomita M., Ishihama Y.; Anal. Sci. 24:161-166(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-892, AND MASSSPECTROMETRY. | |