STYL1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STYL1_HUMAN
• UniProt AC: Q9Y6J8
• Protein Name: Serine/threonine/tyrosine-interacting-like protein 1
• Gene Name: STYXL1
• Organism: Homo sapiens (Human).
• Sequence Length: 313
• Subcellular Localization: Mitochondrion matrix .
• Protein Description: Catalytically inactive phosphatase. [PubMed: 20180778]
• Protein Sequence: MPGLLLCEPTELYNILNQATKLSRLTDPNYLCLLDVRSKWEYDESHVITALRVKKKNNEYLLPESVDLECVKYCVVYDNNSSTLEILLKDDDDDSDSDGDGKDLVPQAAIEYGRILTRLTHHPVYILKGGYERFSGTYHFLRTQKIIWMPQELDAFQPYPIEIVPGKVFVGNFSQACDPKIQKDLKIKAHVNVSMDTGPFFAGDADKLLHIRIEDSPEAQILPFLRHMCHFIEIHHHLGSVILIFSTQGISRSCAAIIAYLMHSNEQTLQRSWAYVKKCKNNMCPNRGLVSQLLEWEKTILGDSITNIMDPLY

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	YNILNQATKLSRLTD HHHHHHHHHHHHCCC	23.82	26074081
21	Ubiquitination	NILNQATKLSRLTDP HHHHHHHHHHHCCCC	47.70	-
38	Phosphorylation	LCLLDVRSKWEYDES EEEEECCCCCCCCHH	41.80	23403867
39 (in isoform 5)	Ubiquitination	-	33.22	21906983
39	Ubiquitination	CLLDVRSKWEYDESH EEEECCCCCCCCHHH	33.22	21906983
39 (in isoform 4)	Ubiquitination	-	33.22	21906983
39 (in isoform 3)	Ubiquitination	-	33.22	21906983
39 (in isoform 2)	Ubiquitination	-	33.22	21906983
39 (in isoform 1)	Ubiquitination	-	33.22	21906983
45	Phosphorylation	SKWEYDESHVITALR CCCCCCHHHEEEEEE	21.84	23403867
49	Phosphorylation	YDESHVITALRVKKK CCHHHEEEEEEEEEC	20.67	24719451
56	Ubiquitination	TALRVKKKNNEYLLP EEEEEEECCCCEECC	60.32	-
60	Phosphorylation	VKKKNNEYLLPESVD EEECCCCEECCCCCC	18.70	28152594
65	Phosphorylation	NEYLLPESVDLECVK CCEECCCCCCCEEEE	20.99	28152594
95	Phosphorylation	LKDDDDDSDSDGDGK ECCCCCCCCCCCCCC	46.11	-
97	Phosphorylation	DDDDDSDSDGDGKDL CCCCCCCCCCCCCCC	47.66	-
102	Ubiquitination	SDSDGDGKDLVPQAA CCCCCCCCCCHHHHH	53.26	-
128 (in isoform 1)	Ubiquitination	-	40.51	21906983
128 (in isoform 2)	Ubiquitination	-	40.51	21906983
128 (in isoform 3)	Ubiquitination	-	40.51	21906983
128	Ubiquitination	HHPVYILKGGYERFS CCCEEEEECCCCCCC	40.51	21906983
137	Phosphorylation	GYERFSGTYHFLRTQ CCCCCCEEEEEEEEC	16.78	22210691
145 (in isoform 1)	Ubiquitination	-	35.23	21906983
145 (in isoform 2)	Ubiquitination	-	35.23	21906983
145	Ubiquitination	YHFLRTQKIIWMPQE EEEEEECEEEEECCC	35.23	2190698
145 (in isoform 3)	Ubiquitination	-	35.23	21906983
180	Ubiquitination	FSQACDPKIQKDLKI HHHCCCHHHCCCCEE	44.51	-
278	Ubiquitination	RSWAYVKKCKNNMCP HHHHHHHHHCCCCCC	40.16	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STYL1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STYL1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STYL1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
AES_HUMAN	AES	physical	17353931
SMC1A_HUMAN	SMC1A	physical	17353931
RS29_HUMAN	RPS29	physical	17353931
ATX10_HUMAN	ATXN10	physical	17353931
EHD4_HUMAN	EHD4	physical	17353931
SERB_HUMAN	PSPH	physical	17353931
ACTS_HUMAN	ACTA1	physical	27880917
MYO1B_HUMAN	MYO1B	physical	27880917
MYO1C_HUMAN	MYO1C	physical	27880917
SPTN1_HUMAN	SPTAN1	physical	27880917
SPTB2_HUMAN	SPTBN1	physical	27880917
VIME_HUMAN	VIM	physical	27880917

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.