SSNA1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SSNA1_HUMAN
• UniProt AC: O43805
• Protein Name: Sjoegren syndrome nuclear autoantigen 1
• Gene Name: SSNA1
• Organism: Homo sapiens (Human).
• Sequence Length: 119
• Subcellular Localization: Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
• Protein Sequence: MTQQGAALQNYNNELVKCIEELCQKREELCRQIQEEEDEKQRLQNEVRQLTEKLARVNENLARKIASRNEFDRTIAETEAAYLKILESSQTLLSVLKREAGNLTKATAPDQKSSGGRDS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MTQQGAALQ ------CCHHHHHHH	29.60	19413330
2	Phosphorylation	------MTQQGAALQ ------CCHHHHHHH	29.60	24043423
11	Phosphorylation	QGAALQNYNNELVKC HHHHHHHHHHHHHHH	13.35	27642862
25	Ubiquitination	CIEELCQKREELCRQ HHHHHHHHHHHHHHH	61.86	-
53	Ubiquitination	EVRQLTEKLARVNEN HHHHHHHHHHHHCHH	42.06	-
78	Phosphorylation	FDRTIAETEAAYLKI HHHHHHHHHHHHHHH	23.15	29978859
82	Phosphorylation	IAETEAAYLKILESS HHHHHHHHHHHHHHH	18.64	29978859
88	Phosphorylation	AYLKILESSQTLLSV HHHHHHHHHHHHHHH	25.05	25219547
89	Phosphorylation	YLKILESSQTLLSVL HHHHHHHHHHHHHHH	20.15	25219547
91	Phosphorylation	KILESSQTLLSVLKR HHHHHHHHHHHHHHH	31.45	25219547
94	Phosphorylation	ESSQTLLSVLKREAG HHHHHHHHHHHHHHC	28.63	25219547
97	Sumoylation	QTLLSVLKREAGNLT HHHHHHHHHHHCCCC	46.14	-
97	Ubiquitination	QTLLSVLKREAGNLT HHHHHHHHHHHCCCC	46.14	21890473
97	Sumoylation	QTLLSVLKREAGNLT HHHHHHHHHHHCCCC	46.14	-
105	Ubiquitination	REAGNLTKATAPDQK HHHCCCCCCCCCCCC	47.08	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SSNA1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SSNA1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SSNA1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SSNA1_HUMAN	SSNA1	physical	25416956
THIOM_HUMAN	TXN2	physical	25416956
TBCD7_HUMAN	TBC1D7	physical	25416956
GOPC_HUMAN	GOPC	physical	25416956
LNX1_HUMAN	LNX1	physical	25416956
TEANC_HUMAN	TCEANC	physical	25416956
SSNA1_HUMAN	SSNA1	physical	21516116
LCA5_HUMAN	LCA5	physical	27173435
KIF3A_HUMAN	KIF3A	physical	27173435

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.