SSBP2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SSBP2_MOUSE
• UniProt AC: Q9CYZ8
• Protein Name: Single-stranded DNA-binding protein 2
• Gene Name: Ssbp2
• Organism: Mus musculus (Mouse).
• Sequence Length: 361
• Subcellular Localization: Nucleus.
• Protein Sequence: MYGKGKSNSSAVPSDSQAREKLALYVYEYLLHVGAQKSAQTFLSEIRWEKNITLGEPPGFLHSWWCVFWDLYCAAPERRETCEHSSEAKAFHDYSAAAAPSPVLGNMPPGDGMPVGPVPPGFFQPFMSPRYPGGPRPPLRIPNQALGGVPGSQPLLPSGMDPTRQQGHPNMGGPMQRMTPPRGMVPLGPQNYGGAMRPPLNALGGPGMPGMNMGPGGGRPWPNPTNANSIPYSSASPGNYVGPPGGGGPPGTPIMPSPADSTNSGDNMYTLMNAVPPGPNRPNFPMGPGSDGPMGGLGGMESHHMNGSLGSGDMDSISKNSPNNMSLSNQPGTPRDDGEMGGNFLNPFQSESYSPSMTMSV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MYGKGKSN -------CCCCCCCC	10.06	-
2	Phosphorylation	------MYGKGKSNS ------CCCCCCCCC	27.78	30635358
6	Acetylation	--MYGKGKSNSSAVP --CCCCCCCCCCCCC	50.37	23806337
7	Phosphorylation	-MYGKGKSNSSAVPS -CCCCCCCCCCCCCC	51.08	30635358
9	Phosphorylation	YGKGKSNSSAVPSDS CCCCCCCCCCCCCCH	27.11	30635358
10	Phosphorylation	GKGKSNSSAVPSDSQ CCCCCCCCCCCCCHH	37.22	30635358
14	Phosphorylation	SNSSAVPSDSQAREK CCCCCCCCCHHHHHH	43.21	30635358
16	Phosphorylation	SSAVPSDSQAREKLA CCCCCCCHHHHHHHH	30.03	30635358
100 (in isoform 2)	Dimethylation	-	34.14	-
106 (in isoform 2)	Dimethylation	-	35.31	-
130	Asymmetric dimethylarginine	FQPFMSPRYPGGPRP CCCCCCCCCCCCCCC	42.86	-
130	Methylation	FQPFMSPRYPGGPRP CCCCCCCCCCCCCCC	42.86	54541589
136	Methylation	PRYPGGPRPPLRIPN CCCCCCCCCCCCCCC	49.06	54541593
136	Asymmetric dimethylarginine	PRYPGGPRPPLRIPN CCCCCCCCCCCCCCC	49.06	-
140	Asymmetric dimethylarginine	GGPRPPLRIPNQALG CCCCCCCCCCCCCCC	48.36	-
321	Phosphorylation	MDSISKNSPNNMSLS HHHCCCCCCCCCCCC	32.51	25521595
326	Phosphorylation	KNSPNNMSLSNQPGT CCCCCCCCCCCCCCC	30.67	22817900
328	Phosphorylation	SPNNMSLSNQPGTPR CCCCCCCCCCCCCCC	26.55	28066266
333	Phosphorylation	SLSNQPGTPRDDGEM CCCCCCCCCCCCCCC	23.10	21082442
350	Phosphorylation	NFLNPFQSESYSPSM CCCCCCCCCCCCCCC	28.96	26643407
352	Phosphorylation	LNPFQSESYSPSMTM CCCCCCCCCCCCCCC	35.84	26643407
353	Phosphorylation	NPFQSESYSPSMTMS CCCCCCCCCCCCCCC	22.13	26643407
354	Phosphorylation	PFQSESYSPSMTMSV CCCCCCCCCCCCCCC	21.56	26643407
356	Phosphorylation	QSESYSPSMTMSV-- CCCCCCCCCCCCC--	22.42	26643407
358	Phosphorylation	ESYSPSMTMSV---- CCCCCCCCCCC----	15.61	27600695
360	Phosphorylation	YSPSMTMSV------ CCCCCCCCC------	18.60	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SSBP2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SSBP2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SSBP2_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SSBP2_MOUSE	Ssbp2	physical	20211142
PYGO1_MOUSE	Pygo1	physical	20211142
SSBP3_MOUSE	Ssbp3	physical	20211142
CERS2_MOUSE	Cers2	physical	20211142
ISL2_MOUSE	Isl2	physical	20211142
SLF1_MOUSE	Ankrd32	physical	20211142
LMO3_MOUSE	Lmo3	physical	20211142
RBTN1_MOUSE	Lmo1	physical	20211142
LMX1A_MOUSE	Lmx1a	physical	20211142

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.