SLX4I_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SLX4I_HUMAN
• UniProt AC: Q5VYV7
• Protein Name: Protein SLX4IP
• Gene Name: SLX4IP
• Organism: Homo sapiens (Human).
• Sequence Length: 408
• Protein Sequence: MASKKFAVKCGNFAVLVDLHILPQGSNKDTSWFSEQKKEEVCLLLKETIDSRVQEYLEVRKQHRPSNAEFTRSNPLSLKGYGFQITAYFLKRGIRLRCIRSTQNAELCVFPDRFVVCVSQLAFSRDLLASQNEDLTERVLHGVSDYFAECAESSLPPSAKLRRNALKEIVKRTETKSSVTSKSQTRRDTVETSSDSVIAEIARRRNDGQASSSPPSESMGQAKDSIKAAESHWGLPVQKLEKVNQTQPEDTSGQQKPHPGERLKTGLLSRSPVCSCESASPCPKQSPRVAKTQQKRRNCSSAEDFDHHGRVSLGSDRLVPREIIVEKSKAVRVLPASELSDPGLLLKQDLAKTTSKEELHVLESLSSRHLMKNNPGQAQQTGLATNTERLSTIQNSPTKKRKKYERGH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
61	Sumoylation	QEYLEVRKQHRPSNA HHHHHHHHHHCCCCC		28112733
61	Ubiquitination	QEYLEVRKQHRPSNA HHHHHHHHHHCCCCC		29967540
66	Phosphorylation	VRKQHRPSNAEFTRS HHHHHCCCCCCCCCC		28555341
73	Phosphorylation	SNAEFTRSNPLSLKG CCCCCCCCCCCCCCC		28555341
77	Phosphorylation	FTRSNPLSLKGYGFQ CCCCCCCCCCCCCEE		28555341
79	Sumoylation	RSNPLSLKGYGFQIT CCCCCCCCCCCEEHH		-
79	Sumoylation	RSNPLSLKGYGFQIT CCCCCCCCCCCEEHH		28112733
130	Phosphorylation	FSRDLLASQNEDLTE HCHHHHHHCCCCHHH		30576142
136	Phosphorylation	ASQNEDLTERVLHGV HHCCCCHHHHHHHHH		23186163
167	Ubiquitination	KLRRNALKEIVKRTE HHHHHHHHHHHHHHC		-
167	Sumoylation	KLRRNALKEIVKRTE HHHHHHHHHHHHHHC		28112733
176	Sumoylation	IVKRTETKSSVTSKS HHHHHCCCCCCCCCC		28112733
181	Phosphorylation	ETKSSVTSKSQTRRD CCCCCCCCCCHHCCH		-
183	Phosphorylation	KSSVTSKSQTRRDTV CCCCCCCCHHCCHHC		-
185	Phosphorylation	SVTSKSQTRRDTVET CCCCCCHHCCHHCCC		-
189	Phosphorylation	KSQTRRDTVETSSDS CCHHCCHHCCCCHHH		29978859
192	Phosphorylation	TRRDTVETSSDSVIA HCCHHCCCCHHHHHH		28270605
193	Phosphorylation	RRDTVETSSDSVIAE CCHHCCCCHHHHHHH		29978859
194	Phosphorylation	RDTVETSSDSVIAEI CHHCCCCHHHHHHHH		29978859
196	Phosphorylation	TVETSSDSVIAEIAR HCCCCHHHHHHHHHH		29978859
211	Phosphorylation	RRNDGQASSSPPSES HCCCCCCCCCCCCHH		30266825
212	Phosphorylation	RNDGQASSSPPSESM CCCCCCCCCCCCHHH		30266825
213	Phosphorylation	NDGQASSSPPSESMG CCCCCCCCCCCHHHH		30266825
216	Phosphorylation	QASSSPPSESMGQAK CCCCCCCCHHHHCHH		30266825
218	Phosphorylation	SSSPPSESMGQAKDS CCCCCCHHHHCHHHH		28450419
225	Phosphorylation	SMGQAKDSIKAAESH HHHCHHHHHHHHHHH		23312004
227	Ubiquitination	GQAKDSIKAAESHWG HCHHHHHHHHHHHCC		29967540
239	Sumoylation	HWGLPVQKLEKVNQT HCCCCHHHHHHHCCC		28112733
239	Sumoylation	HWGLPVQKLEKVNQT HCCCCHHHHHHHCCC		-
242	Sumoylation	LPVQKLEKVNQTQPE CCHHHHHHHCCCCCC		28112733
256	Sumoylation	EDTSGQQKPHPGERL CCCCCCCCCCCCHHH		28112733
265	Phosphorylation	HPGERLKTGLLSRSP CCCHHHCCCCCCCCC		28450419
269	Phosphorylation	RLKTGLLSRSPVCSC HHCCCCCCCCCCCCC		28450419
271	Phosphorylation	KTGLLSRSPVCSCES CCCCCCCCCCCCCCC		28450419
275	Phosphorylation	LSRSPVCSCESASPC CCCCCCCCCCCCCCC		24719451
278	Phosphorylation	SPVCSCESASPCPKQ CCCCCCCCCCCCCCC		28348404
280	Phosphorylation	VCSCESASPCPKQSP CCCCCCCCCCCCCCH		28985074
286	Phosphorylation	ASPCPKQSPRVAKTQ CCCCCCCCHHHHHHH		24114839
291	Sumoylation	KQSPRVAKTQQKRRN CCCHHHHHHHHHHHC		28112733
300	Phosphorylation	QQKRRNCSSAEDFDH HHHHHCCCCCHHCCC		28555341
301	Phosphorylation	QKRRNCSSAEDFDHH HHHHCCCCCHHCCCC		23312004
312	Phosphorylation	FDHHGRVSLGSDRLV CCCCCCEECCCCCCC		21815630
315	Phosphorylation	HGRVSLGSDRLVPRE CCCEECCCCCCCCCC		27794612
340	Phosphorylation	VLPASELSDPGLLLK EECHHHCCCHHEEEH		26714015
347	Sumoylation	SDPGLLLKQDLAKTT CCHHEEEHHHHHHCC		28112733
347	Ubiquitination	SDPGLLLKQDLAKTT CCHHEEEHHHHHHCC		-
353	Phosphorylation	LKQDLAKTTSKEELH EHHHHHHCCCHHHHH		30108239
354	Phosphorylation	KQDLAKTTSKEELHV HHHHHHCCCHHHHHH		30108239
355	Phosphorylation	QDLAKTTSKEELHVL HHHHHCCCHHHHHHH		30108239
356	Sumoylation	DLAKTTSKEELHVLE HHHHCCCHHHHHHHH		28112733
364	Phosphorylation	EELHVLESLSSRHLM HHHHHHHHHHHHHHH		21815630
372	Sumoylation	LSSRHLMKNNPGQAQ HHHHHHHHCCCCHHH		28112733
381	Phosphorylation	NPGQAQQTGLATNTE CCCHHHHHCCCCCHH		26074081
385	Phosphorylation	AQQTGLATNTERLST HHHHCCCCCHHHHHH		26074081
387	Phosphorylation	QTGLATNTERLSTIQ HHCCCCCHHHHHHHC		26074081
391	Phosphorylation	ATNTERLSTIQNSPT CCCHHHHHHHCCCCC		24732914
392	Phosphorylation	TNTERLSTIQNSPTK CCHHHHHHHCCCCCH		25755297
396	Phosphorylation	RLSTIQNSPTKKRKK HHHHHCCCCCHHHHH		30266825
398	Phosphorylation	STIQNSPTKKRKKYE HHHCCCCCHHHHHHC		30266825
399	Sumoylation	TIQNSPTKKRKKYER HHCCCCCHHHHHHCC		28112733

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SLX4I_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SLX4I_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SLX4I_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PAGR1_HUMAN	PAGR1	physical	19596235
BRE1A_HUMAN	RNF20	physical	19596235
FBXW4_HUMAN	FBXW4	physical	19596235
XPF_HUMAN	ERCC4	physical	19596235
SLX4_HUMAN	SLX4	physical	19596235
STK4_HUMAN	STK4	physical	19596235
SYNE2_HUMAN	SYNE2	physical	19596235
CSN7A_HUMAN	COPS7A	physical	19596235
CUL1_HUMAN	CUL1	physical	19596235
RPN1_HUMAN	RPN1	physical	19596235
RINI_HUMAN	RNH1	physical	19596235

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.