| UniProt ID | SIRK_ARATH | |
|---|---|---|
| UniProt AC | O64483 | |
| Protein Name | Senescence-induced receptor-like serine/threonine-protein kinase | |
| Gene Name | SIRK | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 876 | |
| Subcellular Localization |
Membrane Single-pass type I membrane protein. |
|
| Protein Description | Involved in innate immune response of plants.. | |
| Protein Sequence | MAMLKSLSSILFTSFALLFFLVHAQDQSGFISIDCGIPDDSSYNDETTGIKYVSDSAFVDSGTTKRIAAQFQSSGFDRHLLNVRSFPQSKRSCYDVPTPRGKGFKYLIRTRFMYGNYDDLGRVPEFDLYLGVNFWDSVKLDDATTILNKEIITIPLLDNVQVCVVDKNAGTPFLSVLEIRLLLNTTYETPYDALTLLRRLDYSKTGKLPSRYKDDIYDRIWTPRIVSSEYKILNTSLTVDQFLNNGYQPASTVMSTAETARNESLYLTLSFRPPDPNAKFYVYMHFAEIEVLKSNQTREFSIWLNEDVISPSFKLRYLLTDTFVTPDPVSGITINFSLLQPPGEFVLPPIINALEVYQVNEFLQIPTHPQDVDAMRKIKATYRVKKNWQGDPCVPVDYSWEGIDCIQSDNTTNPRVVSLNISFSELRGQIDPAFSNLTSIRKLDLSGNTLTGEIPAFLANLPNLTELNVEGNKLTGIVPQRLHERSKNGSLSLRFGRNPDLCLSDSCSNTKKKNKNGYIIPLVVVGIIVVLLTALALFRRFKKKQQRGTLGERNGPLKTAKRYFKYSEVVNITNNFERVIGKGGFGKVYHGVINGEQVAVKVLSEESAQGYKEFRAEVDLLMRVHHTNLTSLVGYCNEINHMVLIYEYMANENLGDYLAGKRSFILSWEERLKISLDAAQGLEYLHNGCKPPIVHRDVKPTNILLNEKLQAKMADFGLSRSFSVEGSGQISTVVAGSIGYLDPEYYSTRQMNEKSDVYSLGVVLLEVITGQPAIASSKTEKVHISDHVRSILANGDIRGIVDQRLRERYDVGSAWKMSEIALACTEHTSAQRPTMSQVVMELKQIVYGIVTDQENYDDSTKMLTVNLDTEMVPRAR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 646 | Phosphorylation | INHMVLIYEYMANEN HCCCHHHHHHHCCCC | 9.24 | - | |
| 731 | Phosphorylation | VEGSGQISTVVAGSI EECCCCEEEEEECCC | 13.78 | - | |
| 732 | Phosphorylation | EGSGQISTVVAGSIG ECCCCEEEEEECCCC | 22.19 | - | |
| 745 | Phosphorylation | IGYLDPEYYSTRQMN CCCCCHHHHCCCCCC | 14.22 | - | |
| 790 | Phosphorylation | HISDHVRSILANGDI ECCHHHHHHHHCCCH | 22.36 | 19880383 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SIRK_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SIRK_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SIRK_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SUB_ARATH | SUB | physical | 21423366 | |
| Y2289_ARATH | AT2G28960 | physical | 21423366 | |
| PXC3_ARATH | AT2G41820 | physical | 21423366 | |
| HHP2_ARATH | HHP2 | physical | 24833385 | |
| HHP4_ARATH | HHP4 | physical | 24833385 | |
| UBC32_ARATH | UBC32 | physical | 24833385 | |
| UBC34_ARATH | UBC34 | physical | 24833385 | |
| TCMO_ARATH | C4H | physical | 24833385 | |
| CALX2_ARATH | AT5G07340 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| CHX28_ARATH | chx28 | physical | 24833385 | |
| CP21D_ARATH | AT3G66654 | physical | 24833385 | |
| Y5713_ARATH | AT5G67130 | physical | 24833385 | |
| WAK3_ARATH | WAK3 | physical | 24833385 | |
| BET12_ARATH | ATBET12 | physical | 24833385 | |
| BETL2_ARATH | AT1G29060 | physical | 24833385 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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