WAK3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: WAK3_ARATH
• UniProt AC: Q9LMN8
• Protein Name: Wall-associated receptor kinase 3
• Gene Name: WAK3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 741
• Subcellular Localization: Membrane ; Single-pass type I membrane protein .
• Protein Description: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development..
• Protein Sequence: MKFQEGVFLVVIFFLAYTQLVKGQHQPREDCKLKCGNVTIEYPFGISTGCYYPGDDNFNLTCVVEEKLLLFGIIQVTNISHSGHVSVLFERFSECYEQKNETNGTALGYQLGSSFSLSSNNKFTLVGCNALSLLSTFGKQNYSTGCLSLCNSQPEANGRCNGVGCCTTEDFSVPFDSDTFQFGSVRLRNQVNNSLDLFNTSVYQFNPCTYAFLVEDGKFNFDSSKDLKNLRNVTRFPVALDWSIGNQTCEQAGSTRICGKNSSCYNSTTRNGYICKCNEGYDGNPYRSEGCKDIDECISDTHNCSDPKTCRNRDGGFDCKCPSGYDLNSSMSCTRPEYKRTRIFLVIIIGVLVLLLAAICIQHATKQRKYTKLRRQFFEQNGGGMLIQRLSGAGLSNIDFKIFTEEGMKEATNGYDESRILGQGGQGTVYKGILPDNTIVAIKKARLADSRQVDQFIHEVLVLSQINHRNVVKILGCCLETEVPLLVYEFITNGTLFDHLHGSIFDSSLTWEHRLRIAIEVAGTLAYLHSSASIPIIHRDIKTANILLDENLTAKVADFGASKLIPMDKEQLTTMVQGTLGYLDPEYYTTGLLNEKSDVYSFGVVLMELLSGQKALCFERPQASKHLVSYFVSATEENRLHEIIDDQVLNEDNLKEIQEAARIAAECTRLMGEERPRMKEVAAKLEALRVEKTKHKWSDQYPEENEHLIGGHILSAQGETSSSIGYDSIKNVAILDIETGR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	N-linked_Glycosylation	DCKLKCGNVTIEYPF HCCEEECCEEEEECC	36.91	-
59	N-linked_Glycosylation	YPGDDNFNLTCVVEE CCCCCCCCEEEEEEH	40.47	-
78	N-linked_Glycosylation	FGIIQVTNISHSGHV EEEEEEECCCCCCCH	34.60	-
100	N-linked_Glycosylation	SECYEQKNETNGTAL HHHHHHHCCCCCCEE	62.10	-
103	N-linked_Glycosylation	YEQKNETNGTALGYQ HHHHCCCCCCEEEEE	39.37	-
141	N-linked_Glycosylation	LSTFGKQNYSTGCLS HHHHCCCCCCCCCHH	35.89	-
192	N-linked_Glycosylation	VRLRNQVNNSLDLFN EEHHHHCCCCCHHCC	23.70	-
199	N-linked_Glycosylation	NNSLDLFNTSVYQFN CCCCHHCCCCEEECC	38.45	-
232	N-linked_Glycosylation	KDLKNLRNVTRFPVA HHHHHHCCCCCCCEE	42.55	-
246	N-linked_Glycosylation	ALDWSIGNQTCEQAG EEECEECCCCCCCCC	32.11	-
261	N-linked_Glycosylation	STRICGKNSSCYNST CCEECCCCCCCCCCC	25.16	-
266	N-linked_Glycosylation	GKNSSCYNSTTRNGY CCCCCCCCCCCCCCE	36.89	-
303	N-linked_Glycosylation	ECISDTHNCSDPKTC HHHHCCCCCCCCCCC	29.13	-
328	N-linked_Glycosylation	CPSGYDLNSSMSCTR CCCCCCCCCCCCCCC	29.19	-
391	Phosphorylation	GMLIQRLSGAGLSNI EEEEEECCCCCCCCC	28.87	19880383
404	Phosphorylation	NIDFKIFTEEGMKEA CCEEEEECHHHHHHH	36.28	-
488	Phosphorylation	TEVPLLVYEFITNGT CCCCEEEEEHHHCCC	12.70	-
574	Phosphorylation	MDKEQLTTMVQGTLG CCHHHHHHHHHHHHC	24.76	-
579	Phosphorylation	LTTMVQGTLGYLDPE HHHHHHHHHCCCCHH	10.42	-
587	Phosphorylation	LGYLDPEYYTTGLLN HCCCCHHHHCCCCCC	16.11	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of WAK3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of WAK3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of WAK3_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GRP3_ARATH	GRP-3	physical	11335717
UBC34_ARATH	UBC34	physical	24833385
TRXH5_ARATH	TRX5	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.