RSLAB_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RSLAB_HUMAN
• UniProt AC: Q96S79
• Protein Name: Ras-like protein family member 10B
• Gene Name: RASL10B
• Organism: Homo sapiens (Human).
• Sequence Length: 203
• Subcellular Localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side .
• Protein Description: May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure..
• Protein Sequence: MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDFPPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSETPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCARCKHVHAALRFQGALRRNRCAIM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MVSTYRVAVL -----CCCEEEEEEE	20.58	22210691
4	Phosphorylation	----MVSTYRVAVLG ----CCCEEEEEEEC	12.16	22210691
5	Phosphorylation	---MVSTYRVAVLGA ---CCCEEEEEEECC	8.79	22210691
18	Phosphorylation	GARGVGKSAIVRQFL CCCCCCHHHHHHHHH	19.80	-
36	Phosphorylation	FSEVCVPTTARRLYL CCCCCCCCCCCCCCC	16.82	-
118	Phosphorylation	LETRVIGTSETPIII HHHEECCCCCCCEEE	16.56	30624053
119	Phosphorylation	ETRVIGTSETPIIIV HHEECCCCCCCEEEE	33.97	30624053
121	Phosphorylation	RVIGTSETPIIIVGN EECCCCCCCEEEECC	21.39	30624053
200	Methylation	GALRRNRCAIM---- HHHHCCCEECC----	3.25	-
200	Geranylgeranylation	GALRRNRCAIM---- HHHHCCCEECC----	3.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RSLAB_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RSLAB_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RSLAB_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
SAHH3_HUMAN	AHCYL2	physical	28514442
MMAD_HUMAN	MMADHC	physical	28514442
F192A_HUMAN	FAM192A	physical	28514442
PSME3_HUMAN	PSME3	physical	28514442
SAHH2_HUMAN	AHCYL1	physical	28514442
ZN507_HUMAN	ZNF507	physical	28514442
MK09_HUMAN	MAPK9	physical	28514442
CH60_HUMAN	HSPD1	physical	28514442
PSMG3_HUMAN	PSMG3	physical	28514442
NDUF7_HUMAN	NDUFAF7	physical	28514442
LONM_HUMAN	LONP1	physical	28514442
TARB1_HUMAN	TARBP1	physical	28514442
UBB_HUMAN	UBB	physical	28514442
PASK_HUMAN	PASK	physical	28514442
NDUS6_HUMAN	NDUFS6	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.