RPP14_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RPP14_HUMAN
• UniProt AC: O95059
• Protein Name: Ribonuclease P protein subunit p14
• Gene Name: RPP14
• Organism: Homo sapiens (Human).
• Sequence Length: 124
• Subcellular Localization: Nucleus .
• Protein Description: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends..
• Protein Sequence: MPAPAATYERVVYKNPSEYHYMKVCLEFQDCGVGLNAAQFKQLLISAVKDLFGEVDAALPLDILTYEEKTLSAILRICSSGLVKLWSSLTLLGSYKGKKCAFRVIQVSPFLLALSGNSRELVLD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MPAPAATYERVVYKN CCCCCCEEEEEEECC	9.30	27642862
17	Phosphorylation	RVVYKNPSEYHYMKV EEEECCHHHCCEEEE	61.25	-
19	Phosphorylation	VYKNPSEYHYMKVCL EECCHHHCCEEEEEH	11.55	-
79	Phosphorylation	SAILRICSSGLVKLW HHHHHHHHHCHHHHH	25.68	29083192
80	Phosphorylation	AILRICSSGLVKLWS HHHHHHHHCHHHHHH	31.56	29083192
87	Phosphorylation	SGLVKLWSSLTLLGS HCHHHHHHHCHHHCC	26.38	29083192
88	Phosphorylation	GLVKLWSSLTLLGSY CHHHHHHHCHHHCCC	17.50	29083192
90	Phosphorylation	VKLWSSLTLLGSYKG HHHHHHCHHHCCCCC	23.14	29083192
94	Phosphorylation	SSLTLLGSYKGKKCA HHCHHHCCCCCCCCE	24.52	29083192
95	Phosphorylation	SLTLLGSYKGKKCAF HCHHHCCCCCCCCEE	23.20	29083192

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RPP14_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RPP14_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RPP14_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPP30_HUMAN	RPP30	physical	15096576
RPP40_HUMAN	RPP40	physical	15096576
IGS21_HUMAN	IGSF21	physical	16169070
DOCK7_HUMAN	DOCK7	physical	21900206
A2MG_HUMAN	A2M	physical	21900206
MSH2_HUMAN	MSH2	physical	21900206
WIZ_HUMAN	WIZ	physical	21900206
KMT2B_HUMAN	KMT2B	physical	21900206
PSME1_HUMAN	PSME1	physical	21900206
ATPB_HUMAN	ATP5B	physical	21900206
CAPZB_HUMAN	CAPZB	physical	21900206
KPYM_HUMAN	PKM	physical	21900206
NOVA1_HUMAN	NOVA1	physical	21900206

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.