| UniProt ID | RPE_HUMAN | |
|---|---|---|
| UniProt AC | Q96AT9 | |
| Protein Name | Ribulose-phosphate 3-epimerase | |
| Gene Name | RPE | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 228 | |
| Subcellular Localization | ||
| Protein Description | Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.. | |
| Protein Sequence | MASGCKIGPSILNSDLANLGAECLRMLDSGADYLHLDVMDGHFVPNITFGHPVVESLRKQLGQDPFFDMHMMVSKPEQWVKPMAVAGANQYTFHLEATENPGALIKDIRENGMKVGLAIKPGTSVEYLAPWANQIDMALVMTVEPGFGGQKFMEDMMPKVHWLRTQFPSLDIEVDGGVGPDTVHKCAEAGANMIVSGSAIMRSEDPRSVINLLRNVCSEAAQKRSLDR | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MASGCKIGP ------CCCCCCCCH | 18.03 | 22814378 | |
| 3 | Phosphorylation | -----MASGCKIGPS -----CCCCCCCCHH | 43.34 | - | |
| 10 | Phosphorylation | SGCKIGPSILNSDLA CCCCCCHHHHCHHHH | 34.20 | - | |
| 14 | Phosphorylation | IGPSILNSDLANLGA CCHHHHCHHHHHHHH | 30.47 | - | |
| 23 | Glutathionylation | LANLGAECLRMLDSG HHHHHHHHHHHHHCC | 2.64 | 22555962 | |
| 56 | Phosphorylation | FGHPVVESLRKQLGQ CCCHHHHHHHHHHCC | 23.12 | 24719451 | |
| 159 | Ubiquitination | FMEDMMPKVHWLRTQ HHHHHHHHCHHHHCC | 28.92 | - | |
| 169 | Phosphorylation | WLRTQFPSLDIEVDG HHHCCCCCCEEEECC | 39.71 | 30624053 | |
| 194 | Ubiquitination | AEAGANMIVSGSAIM HHHCCCEEEECCCCC | 1.93 | - | |
| 196 | Phosphorylation | AGANMIVSGSAIMRS HCCCEEEECCCCCCC | 18.99 | - | |
| 198 | Phosphorylation | ANMIVSGSAIMRSED CCEEEECCCCCCCCC | 13.71 | - | |
| 203 | Phosphorylation | SGSAIMRSEDPRSVI ECCCCCCCCCHHHHH | 29.04 | - | |
| 218 | Phosphorylation | NLLRNVCSEAAQKRS HHHHHHHHHHHHHHC | 26.45 | - | |
| 223 | Ubiquitination | VCSEAAQKRSLDR-- HHHHHHHHHCCCC-- | 38.95 | - | |
| 223 | 2-Hydroxyisobutyrylation | VCSEAAQKRSLDR-- HHHHHHHHHCCCC-- | 38.95 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RPE_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RPE_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RPE_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| RPE_HUMAN | RPE | physical | 16189514 | |
| RPE_HUMAN | RPE | physical | 25416956 | |
| CLUS_HUMAN | CLU | physical | 26186194 | |
| APOD_HUMAN | APOD | physical | 26186194 | |
| PUR8_HUMAN | ADSL | physical | 26344197 | |
| ALDH2_HUMAN | ALDH2 | physical | 26344197 | |
| SSDH_HUMAN | ALDH5A1 | physical | 26344197 | |
| ALDOB_HUMAN | ALDOB | physical | 26344197 | |
| IDE_HUMAN | IDE | physical | 26344197 | |
| IMPA2_HUMAN | IMPA2 | physical | 26344197 | |
| MP2K1_HUMAN | MAP2K1 | physical | 26344197 | |
| MP2K2_HUMAN | MAP2K2 | physical | 26344197 | |
| NRBP_HUMAN | NRBP1 | physical | 26344197 | |
| NTF2_HUMAN | NUTF2 | physical | 26344197 | |
| PGK2_HUMAN | PGK2 | physical | 26344197 | |
| PPCS_HUMAN | PPCS | physical | 26344197 | |
| TALDO_HUMAN | TALDO1 | physical | 26344197 | |
| TEC_HUMAN | TEC | physical | 26344197 | |
| TRAP1_HUMAN | TRAP1 | physical | 26344197 | |
| UPP1_HUMAN | UPP1 | physical | 26344197 | |
| APOD_HUMAN | APOD | physical | 28514442 | |
| CLUS_HUMAN | CLU | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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