dbPTM

OPA_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OPA_DROME
UniProt AC	P39768
Protein Name	Pair-rule protein odd-paired
Gene Name	opa
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	609
Subcellular Localization	Nucleus .
Protein Description	Transcription factor essential for parasegmental subdivision of the embryo. It is involved in the activation of wingless (wg) in odd parasegments. It is also required for the timely activation of wg in the remaining parasegments and for the timely activation of engrailed (en) in all parasegments..
Protein Sequence	MMMNAFIEPAQHHLASYGLRMSPNTTASNSNAQQQQQQQLEMTQQQQQQQQQQQQQQQQDQESAAATAAAYQNSGYGHFNSYASRDFLLGRREAEYGVAGSAGQASAAADSMLFSGFPAQAAELGSGFGQHPFHSHHHHHQMRMGMADAYAAGHPYNHHGNFPTAAVHHPVVHHPSHHAMSAMHPAGAGAFLRYMRHQPASSASSVKQEMQCLWIDPDQPGLVPPGGRKTCNKVFHSMHEIVTHLTVEHVGGPECTTHACFWVGCSRNGRPFKAKYKLVNHIRVHTGEKPFACPHPGCGKVFARSENLKIHKRTHTGEKPFKCEHEGCDRRFANSSDRKKHSHVHTSDKPYNCRINGCDKSYTHPSSLRKHMKVHGNVDEKSPSHGYDSEGEESSSSSIITGGAQTPPSTRLDGSAGSSSGVSSLSGGSGIKSSPHSIKSEPNPMHSVHLGASSSGSSSTASSSASHLLQHQQHQHQQQQQQQQHQQQAQQQQQLTAHPSDPKSSPALQLMAASASAYLPPPLGPPPSHHHHPHHHQAAPSPGAAAASASMLHHNHHLLYHPAAQHHPPSDWYHTTAPSGSAEAMNPLNHFGHHHHHHHLMHPGAATAY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
316	Phosphorylation	KIHKRTHTGEKPFKC EEECCCCCCCCCCCC	46.56	22817900
429	Phosphorylation	VSSLSGGSGIKSSPH CCCCCCCCCCCCCCC	40.65	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OPA_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OPA_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OPA_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ELBOW_DROME	elB	physical	14605208
SINAL_DROME	sinah	physical	14605208
CAND_DROME	sol	physical	14605208
MS84A_DROME	Mst84Da	physical	14605208
MS87F_DROME	Mst87F	physical	14605208
UBP30_DROME	CG3016	physical	14605208
RS8_DROME	RpS8	physical	14605208
ADT_DROME	sesB	physical	14605208

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OPA_DROME

Related Literatures of Post-Translational Modification