ADT_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ADT_DROME
• UniProt AC: Q26365
• Protein Name: ADP,ATP carrier protein
• Gene Name: sesB
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 312
• Subcellular Localization: Mitochondrion inner membrane; Multi-pass membrane protein.
• Protein Description: Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane..
• Protein Sequence: MGNISASITSQSKMGKDFDAVGFVKDFAAGGISAAVSKTAVAPIERVKLLLQVQHISKQISPDKQYKGMVDCFIRIPKEQGFSSFWRGNLANVIRYFPTQALNFAFKDKYKQVFLGGVDKNTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADTGKGGQREFTGLGNCLTKIFKSDGIVGLYRGFGVSVQGIIIYRAAYFGFYDTARGMLPDPKNTPIYISWAIAQVVTTVAGIVSYPFDTVRRRMMMQSGRKATEVIYKNTLHCWATIAKQEGTGAFFKGAFSNILRGTGGAFVLVLYDEIKKVL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Acetylation	TSQSKMGKDFDAVGF CCHHHCCCCCCHHEE	52.29	21791702
37	Phosphorylation	GGISAAVSKTAVAPI CCCCCCCCCCCCCCH	21.40	27794539
38	Acetylation	GISAAVSKTAVAPIE CCCCCCCCCCCCCHH	33.63	21791702
64	Acetylation	SKQISPDKQYKGMVD HHHCCCCHHCCCCEE	59.93	21791702
107	Acetylation	QALNFAFKDKYKQVF HHHHHHCHHHCCEEE	50.29	21791702
111	Acetylation	FAFKDKYKQVFLGGV HHCHHHCCEEEECCC	45.81	21791702
120	Acetylation	VFLGGVDKNTQFWRY EEECCCCCCCHHHHH	60.53	21791702
162	Acetylation	RLAADTGKGGQREFT HHHHCCCCCCCEECC	63.06	21791702
180	Acetylation	NCLTKIFKSDGIVGL HHHHHHHHCCCCEEE	51.62	21791702
286	Acetylation	EGTGAFFKGAFSNIL CCCCHHHHHHHHHHH	42.76	21791702

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ADT_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ADT_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ADT_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CAPZB_DROME	cpb	physical	14605208
HSP23_DROME	Hsp23	physical	14605208
C4AC1_DROME	Cyp4ac1	physical	22036573
SCNA_DROME	para	genetic	15281071
NDKA_DROME	awd	genetic	14668379
DYN_DROME	shi	genetic	15281071
ATNA_DROME	Atpalpha	genetic	15281071
CASP1_DROME	Dcp-1	physical	24862573
SRA_DROME	sra	physical	16222229

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.