MLO6_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MLO6_ARATH
• UniProt AC: Q94KB7
• Protein Name: MLO-like protein 6
• Gene Name: MLO6
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 583
• Subcellular Localization: Membrane; Multi-pass membrane protein.
• Protein Description: May be involved in modulation of pathogen defense and leaf cell death. Activity seems to be regulated by Ca(2+)-dependent calmodulin binding and seems not to require heterotrimeric G proteins (By similarity)..
• Protein Sequence: MADQVKEKTLEETSTWAVAVVCFVLLLISIVIEKLIHKIGSWFKKKNKKALYEALEKVKAELMLMGFISLLLTIGQGYISNICIPKNIAASMHPCSASEEARKYGKKDVPKEDEEENLRRKLLQLVDSLIPRRSLATKGYDKCAEKGKVAFVSAYGMHQLHIFIFVLAVCHVIYCIVTYALGKTKMRRWKKWEEETKTIEYQYSHDPERFRFARDTSFGRRHLSFWSKSTITLWIVCFFRQFFRSVTKVDYLTLRHGFIMAHLAPGSDARFDFRKYIQRSLEEDFKTIVEINPVIWFIAVLFLLTNTNGLNSYLWLPFIPFIVILIVGTKLQVIITKLGLRIQEKGDVVKGTPLVQPGDHFFWFGRPRFILFLIHLVLFTNAFQLAFFVWSTYEFGLKNCFHESRVDVIIRISIGLLVQILCSYVTLPLYALVTQMGSKMKPTVFNERVATALKSWHHTAKKNIKHGRTSESTTPFSSRPTTPTHGSSPIHLLRNAPHKRSRSVDESFANSFSPRNSDFDSWDPESQHETAETSNSNHRSRFGEEESEKKFVSSSVELPPGPGQIRTQHEISTISLRDFSFKR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
501	Phosphorylation	RNAPHKRSRSVDESF HCCCCCCCCCCCHHH	33.44	23776212
503	Phosphorylation	APHKRSRSVDESFAN CCCCCCCCCCHHHHH	34.86	23776212
507	Phosphorylation	RSRSVDESFANSFSP CCCCCCHHHHHCCCC	25.79	23776212
511	Phosphorylation	VDESFANSFSPRNSD CCHHHHHCCCCCCCC	24.54	23776212
513	Phosphorylation	ESFANSFSPRNSDFD HHHHHCCCCCCCCCC	23.83	23776212
567	Phosphorylation	PGPGQIRTQHEISTI CCCCCEECCEEEEEE	35.59	30407730
572	Phosphorylation	IRTQHEISTISLRDF EECCEEEEEEECHHC	19.39	30407730
573	Phosphorylation	RTQHEISTISLRDFS ECCEEEEEEECHHCC	21.90	30407730
575	Phosphorylation	QHEISTISLRDFSFK CEEEEEEECHHCCCC	19.90	19880383
580	Phosphorylation	TISLRDFSFKR---- EEECHHCCCCC----	33.86	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MLO6_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MLO6_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MLO6_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MLO6_ARATH	MLO6	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
UBC32_ARATH	UBC32	physical	24833385
ACBP6_ARATH	ACBP6	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
MSBP2_ARATH	MAPR3	physical	24833385
PPA3_ARATH	PAP3	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
WAK3_ARATH	WAK3	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.