HXK3_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HXK3_RAT
• UniProt AC: P27926
• Protein Name: Hexokinase-3
• Gene Name: Hk3
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 924
• Protein Sequence: MAAIEPSGLHPGERDSSCPQEGIPRPSGSLELAQEYLQQFKVTMTQLQQIQASLLCSMEQALKGQDSPAPSVRMLPTYVRSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTKEHSVETRSQEFVIPQEVILGAGQQLFDFAARCLSEFLDAYPVENQGLKLGFNFSFPCHQTGLDKSTLISWTKGFRCSGVEGQDVVQLLRDAIQRQGTYNIDVVAMVNDTVGTMMGCELGTRPCEVGLIVDTGTNACYMEEARHVAALDEDRGRTCVSIEWGSFYDEEALGPVLTTFDDALDHESLVPGAQRFEKMIGGLYLGELVRLVLVHLSQHGVLFGGCASPALLSQNSILLEHVAKMEDPATGIAHVHTVLQGLGLSPQASDAELVQRVCMAVCTRAAQLCASALAAVLSRLQHSREQQTLHVAVATGGRVFEWHPRFLCILKETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLATHRRILEETLAPFQLSLEQLTAVQAQMREAMIRGLQGESSSLRMLPTYVRATPDGSERGDFLALDLGGTNFRVLLVRVAEGSVQITNQVYSIPEYVAQGSGQKLFDHIVDCIVDFQKRQGLSGQSLPLGFTFSFPCKQLGLDQGILLNWTKGFNASGCEGQDVVYLLREAIRRRQAVELNVVAIVNDTVGTMMSCGYDDPCCEMGLIVGTGTNACYMEELRNVASVPGDSGHMCINMEWGAFGDDGSLSMLGTCFDASVDQASINPGKQRFEKMISGMYLGEIVRHILLHLTSLGVLFRGQKTQCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLTLTSDDALMVLEVCQAVSRRAAQLCGAGVAAVVEKIRENRGLQELTVSVGVDGTLYKLHPHFSRLVSVTVRKLAPQCTVTFLQSEDGSGKGAALVTRVACRLTQMACV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
77	Phosphorylation	PSVRMLPTYVRSTPH CCCCCCCEEECCCCC	30.59	16641100
86	Phosphorylation	VRSTPHGTEQGDFLV ECCCCCCCCCCCEEE	23.31	16641100
99	Phosphorylation	LVLELGATGASLRVL EEEEECCCCCEEEEE	31.33	16641100
756	Phosphorylation	EKMISGMYLGEIVRH HHHHCHHHHHHHHHH	18.32	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HXK3_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HXK3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HXK3_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PTGDS_HUMAN	PTGDS	physical	11068878
LEP_HUMAN	LEP	physical	11068878
GRN_HUMAN	GRN	physical	11068878
IBP4_HUMAN	IGFBP4	physical	11068878
ZBT17_HUMAN	ZBTB17	physical	11068878
PTGDS_RAT	Ptgds	physical	11068878
IBP4_RAT	Igfbp4	physical	11068878
GRN_RAT	Grn	physical	11068878
LEP_RAT	Lep	physical	11068878

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.