dbPTM

HMG2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HMG2_DROME
UniProt AC	Q24537
Protein Name	High mobility group protein DSP1
Gene Name	Dsp1
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	393
Subcellular Localization	Nucleus. Chromosome.
Protein Description	Binds preferentially single-stranded DNA and unwinds double-stranded DNA..
Protein Sequence	MEHFHQIQQTIQHYQQQLAAQQQQQVQQQQLQQHQVVVQQNQQQAHQNSSNTTAGVGTQQLFTYKMASSFPNPATTMAQVVATSNAAGTTGYDYRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLQHQQQQQQQQQQQQQQQHQQQQQMQQQQQQQNVINSASPMSRVKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYEAEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASMQAQAQKAALLAAAAQQQHQQLEEQHDDDDGDGDDDENQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
205	Phosphorylation	KKKHPDETVIFAEFS HHHCCCCCEEHHHHH	26.70	21082442
221	Phosphorylation	KCAERWKTMVDKEKK HHHHHHHHHHHHHHH	18.57	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HMG2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HMG2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HMG2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ASH1_DROME	ash1	genetic	11139505
PC_DROME	Pc	genetic	11139505
SCR_DROME	Scr	genetic	11139505
TRX_DROME	trx	genetic	11139505
UBX_DROME	Ubx	genetic	11139505
DORS_DROME	dl	physical	10606643
DDX17_DROME	Rm62	physical	20196121

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HMG2_DROME

Related Literatures of Post-Translational Modification