HGH1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: HGH1_HUMAN
• UniProt AC: Q9BTY7
• Protein Name: Protein HGH1 homolog
• Gene Name: HGH1
• Organism: Homo sapiens (Human).
• Sequence Length: 390
• Protein Sequence: MGEAGAGAGASGGPEASPEAEVVKLLPFLAPGARADLQAAAVRHVLALTGCGPGRALLAGQAALLQALMELAPASAPARDAARALVNLAADPGLHETLLAADPGLPARLMGRALDPQWPWAEEAAAALANLSREPAPCAALMAALAAAEPADSGLERLVRALCTPGYNARAPLHYLAPLLSNLSQRPAARAFLLDPDRCVVQRLLPLTQYPDSSVRRGGVVGTLRNCCFEHRHHEWLLGPEVDILPFLLLPLAGPEDFSEEEMERLPVDLQYLPPDKQREPDADIRKMLVEAIMLLTATAPGRQQVRDQGAYLILRELHSWEPEPDVRTACEKLIQVLIGDEPERGMENLLEVQVPEDVEQQLQQLDCREQEQLERELAPEPWVERATPT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MGEAGAGAG ------CCCCCCCCC		19413330
11	Phosphorylation	AGAGAGASGGPEASP CCCCCCCCCCCCCCC		23186163
17	Phosphorylation	ASGGPEASPEAEVVK CCCCCCCCCHHHHHH		21815630
24	Ubiquitination	SPEAEVVKLLPFLAP CCHHHHHHHHHHCCC		-
24	Ubiquitination	SPEAEVVKLLPFLAP CCHHHHHHHHHHCCC		-
49	Phosphorylation	VRHVLALTGCGPGRA HHHHHHHHCCCHHHH		-
213	Phosphorylation	PLTQYPDSSVRRGGV CHHCCCCCCCCCCCH		28122231
214	Phosphorylation	LTQYPDSSVRRGGVV HHCCCCCCCCCCCHH		23186163
217	Methylation	YPDSSVRRGGVVGTL CCCCCCCCCCHHHHH		-
223	Phosphorylation	RRGGVVGTLRNCCFE CCCCHHHHHHHHCHH		-
297	Phosphorylation	VEAIMLLTATAPGRQ HHHHHHHHHCCCCHH		26546556
320	Phosphorylation	LILRELHSWEPEPDV EEEHHHHHCCCCCCH		25599653
333	Ubiquitination	DVRTACEKLIQVLIG CHHHHHHHHHHHHHC		-
333	Ubiquitination	DVRTACEKLIQVLIG CHHHHHHHHHHHHHC		-
388	Phosphorylation	EPWVERATPT----- CCCHHCCCCC-----		25159151
390	Phosphorylation	WVERATPT------- CHHCCCCC-------		21712546

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of HGH1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of HGH1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of HGH1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TM256_HUMAN	TMEM256	physical	16169070
MOD5_HUMAN	TRIT1	physical	16169070
APOM_HUMAN	APOM	physical	16169070
GASP1_HUMAN	GPRASP1	physical	16169070
TF3C1_HUMAN	GTF3C1	physical	16169070
DPOA2_HUMAN	POLA2	physical	16169070
MED31_HUMAN	MED31	physical	16169070
PTN_HUMAN	PTN	physical	16169070
RFA1_HUMAN	RPA1	physical	16169070
HGS_HUMAN	HGS	physical	22863883
SLK_HUMAN	SLK	physical	22863883
TTC4_HUMAN	TTC4	physical	22863883

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.