TM256_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TM256_HUMAN
• UniProt AC: Q8N2U0
• Protein Name: Transmembrane protein 256
• Gene Name: TMEM256
• Organism: Homo sapiens (Human).
• Sequence Length: 113
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MAGPAAAFRRLGALSGAAALGFASYGAHGAQFPDAYGKELFDKANKHHFLHSLALLGVPHCRKPLWAGLLLASGTTLFCTSFYYQALSGDPSIQTLAPAGGTLLLLGWLALAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
15	Phosphorylation	FRRLGALSGAAALGF HHHHHHHHHHHHHCH		-
25	Phosphorylation	AALGFASYGAHGAQF HHHCHHHHCCCCCCC		-
36	Phosphorylation	GAQFPDAYGKELFDK CCCCCCHHHHHHHHH		-
43	Acetylation	YGKELFDKANKHHFL HHHHHHHHHCHHHHH		25825284
43	Ubiquitination	YGKELFDKANKHHFL HHHHHHHHHCHHHHH		29967540
43	2-Hydroxyisobutyrylation	YGKELFDKANKHHFL HHHHHHHHHCHHHHH		-
102	Phosphorylation	TLAPAGGTLLLLGWL HCCCCCHHHHHHHHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TM256_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TM256_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TM256_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
G6PI_HUMAN	GPI	physical	22939629
VDAC3_HUMAN	VDAC3	physical	22939629

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.