ERMAP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ERMAP_HUMAN
• UniProt AC: Q96PL5
• Protein Name: Erythroid membrane-associated protein
• Gene Name: ERMAP
• Organism: Homo sapiens (Human).
• Sequence Length: 475
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Cytoplasm .
• Protein Description: Possible role as a cell-adhesion or receptor molecule of erythroid cells..
• Protein Sequence: MEMASSAGSWLSGCLIPLVFLRLSVHVSGHAGDAGKFHVALLGGTAELLCPLSLWPGTVPKEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSAVALAVILPVLVLLIMVCLCLIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSELKLKRAAANSGWRRARLHFVAVTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSEYFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQTSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNTAPLVICSELHKSEESIVPRPEGKGHANGDVSLKVNSSLLPPKAPELKDIILSLPPDLGPALQELKAPSF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MEMASSAGSWLSG --CCCCCHHHHHHHH	27.41	-
9	Phosphorylation	EMASSAGSWLSGCLI CCCCHHHHHHHHCHH	25.26	-
12	Phosphorylation	SSAGSWLSGCLIPLV CHHHHHHHHCHHHHH	22.62	-
94	Phosphorylation	DEDLMPEYKGRTVLV CCCCCCHHCCEEEEE	16.93	-
132	N-linked_Glycosylation	RCLIQVGNLSKEDTV EEEEEECCCCCCCEE	42.14	UniProtKB CARBOHYD
134	Phosphorylation	LIQVGNLSKEDTVIL EEEECCCCCCCEEEE	37.69	-
188	Phosphorylation	RAKEKLLYEHVTEVD HHHHHHHHHHHHHHH	17.90	27642862
303	Phosphorylation	EVYVGDKTKWILGVC EEEECCCEEEEEEEC	36.03	-
406	Phosphorylation	LHDGGKNTAPLVICS CCCCCCCCCCEEEEC	32.89	23186163
413	Phosphorylation	TAPLVICSELHKSEE CCCEEEECCCCCCCC	31.88	29514088
418	Phosphorylation	ICSELHKSEESIVPR EECCCCCCCCCCCCC	35.53	21082442
421	Phosphorylation	ELHKSEESIVPRPEG CCCCCCCCCCCCCCC	25.49	29514088
437	Phosphorylation	GHANGDVSLKVNSSL CCCCCCEEEEECHHC	27.49	19651622
474	Phosphorylation	LQELKAPSF------ HHHHCCCCC------	48.74	29691806

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ERMAP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ERMAP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ERMAP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EVI1_HUMAN	MECOM	physical	28514442
F199X_HUMAN	FAM199X	physical	28514442
DOCK4_HUMAN	DOCK4	physical	28514442
UBP34_HUMAN	USP34	physical	28514442
ELMO2_HUMAN	ELMO2	physical	28514442
CWC22_HUMAN	CWC22	physical	28514442
AP3B1_HUMAN	AP3B1	physical	28514442
ZCH18_HUMAN	ZC3H18	physical	28514442
GEMI2_HUMAN	GEMIN2	physical	28514442
AKA11_HUMAN	AKAP11	physical	28514442
CDC73_HUMAN	CDC73	physical	28514442
UBR4_HUMAN	UBR4	physical	28514442
KAP1_HUMAN	PRKAR1B	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.