ELMD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELMD1_HUMAN
• UniProt AC: Q8N336
• Protein Name: ELMO domain-containing protein 1
• Gene Name: ELMOD1
• Organism: Homo sapiens (Human).
• Sequence Length: 334
• Protein Description: Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family..
• Protein Sequence: MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREAYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
45	Ubiquitination	QRICYNTKPGASRTM EHHHCCCCCCCCCCE	37.50	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELMD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELMD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELMD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SBP1_HUMAN	SELENBP1	physical	26186194
LRC15_HUMAN	LRRC15	physical	26186194
PKP3_HUMAN	PKP3	physical	26186194
LEG3_HUMAN	LGALS3	physical	26186194
DSG4_HUMAN	DSG4	physical	26186194
LRC15_HUMAN	LRRC15	physical	28514442
LDHC_HUMAN	LDHC	physical	28514442
PKP3_HUMAN	PKP3	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.