DER22_ARATH - dbPTM
DER22_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DER22_ARATH
UniProt AC Q9ZS88
Protein Name Derlin-2.2
Gene Name DER2.2
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 244
Subcellular Localization Endoplasmic reticulum membrane
Multi-pass membrane protein.
Protein Description May be involved in the degradation process of specific misfolded endoplasmic reticulum (ER) luminal proteins..
Protein Sequence MAQAVEEWYKQMPIITRSYLTAAVITTVGCSLDIISPYNLYLNPTLVVKQYQYWRLVTNFLYFRKMDLDFMFHMFFLARYCKLLEENSFRGKTADFLYMLLFGASVLTGIVLIGGMIPYLSASFAKIIFLSNSLTFMMVYVWSKQNPYIHMSFLGLFTFTAAYLPWVLLGFSILVGASAWVDLLGMIAGHAYYFLAEVYPRMTNRRPLKTPSFLKALFADEPVVVARPEDVRFAAAPFDEIHQD
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of DER22_ARATH !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DER22_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DER22_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DER22_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HHP4_ARATHHHP4physical
24833385
MHX_ARATHMHXphysical
24833385
UBC34_ARATHUBC34physical
24833385
FEI1_ARATHFEI1physical
24833385
TRXH5_ARATHTRX5physical
24833385
CNIH1_ARATHAT3G12180physical
24833385
DER22_ARATHDER2.2physical
24833385
DERL1_ARATHDER1physical
24833385
CP21D_ARATHAT3G66654physical
24833385
SPCS1_ARATHAT2G22425physical
24833385
PAM74_ARATHAT5G59650physical
24833385
VA723_ARATHVAMP723physical
24833385
BETL2_ARATHAT1G29060physical
24833385
TBL18_ARATHTBL18physical
24833385

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DER22_ARATH

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Related Literatures of Post-Translational Modification

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