CRK14_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRK14_ARATH
• UniProt AC: Q8H199
• Protein Name: Cysteine-rich receptor-like protein kinase 14
• Gene Name: CRK14
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 658
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MELKNLFPIFWFVLVGFAVVSAQECGKTGFFVPQSRYETNRGLLLSSLPSNVSARGGFYNSSIGQGPDRVYALGMCIEGAEPDVCSDCIEYASNLLLDTCLNQTEGLAWPEKRILCMVRYSNSSFFGSLKAEPHFYIHNVDDITSNLTEFDQVWEELARRMIASTTSPSSKRKYYAADVAALTAFQIIYALMQCTPDLSLEDCHICLRQSVGDYETCCNGKQGGIVYRASCVFRWELFPFSEAFSRISLAPPPQSPAFPTLPAVTNTATKKGSITISIGIVWAIIIPTVIVVFLVLLALGFVVYRRRKSYQGSSTDITITHSLQFDFKAIEDATNKFSESNIIGRGGFGEVFMGVLNGTEVAIKRLSKASRQGAREFKNEVVVVAKLHHRNLVKLLGFCLEGEEKILVYEFVPNKSLDYFLFDPTKQGQLDWTKRYNIIRGITRGILYLHQDSRLTIIHRDLKASNILLDADMNPKIADFGMARIFGIDQSGANTKKIAGTRGYMPPEYVRQGQFSTRSDVYSFGVLVLEIICGRNNRFIHQSDTTVENLVTYAWRLWRNDSPLELVDPTISENCETEEVTRCIHIALLCVQHNPTDRPSLSTINMMLINNSYVLPDPQQPGFFFPIISNQERDGLDSMNRSNPQTINDVTITDFEPR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	N-linked_Glycosylation	LLSSLPSNVSARGGF EHHCCCCCCCCCCCC	29.80	-
60	N-linked_Glycosylation	SARGGFYNSSIGQGP CCCCCCCCCCCCCCC	27.33	-
102	N-linked_Glycosylation	LLLDTCLNQTEGLAW HHHHHHCCCCCCCCC	49.20	-
122	N-linked_Glycosylation	LCMVRYSNSSFFGSL EEEEEECCCCCCCCC	32.51	-
146	N-linked_Glycosylation	NVDDITSNLTEFDQV CHHHHHCCCHHHHHH	42.19	-
409	Phosphorylation	GEEKILVYEFVPNKS CCCEEEEEEECCCCC	10.54	-
465	Phosphorylation	IHRDLKASNILLDAD EECCHHHCCEEECCC	23.86	-
495	Phosphorylation	IDQSGANTKKIAGTR CCCCCCCCCCCCCCC	32.93	25561503
501	Phosphorylation	NTKKIAGTRGYMPPE CCCCCCCCCCCCCHH	16.34	-
509	Phosphorylation	RGYMPPEYVRQGQFS CCCCCHHHHHCCCCC	13.50	-
642	Phosphorylation	GLDSMNRSNPQTIND CHHHCCCCCCCCCCC	48.10	30291188
646	Phosphorylation	MNRSNPQTINDVTIT CCCCCCCCCCCEEEE	24.01	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRK14_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRK14_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRK14_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
POP3_ARATH	HS1	physical	24833385
FEI1_ARATH	FEI1	physical	24833385
ACBP6_ARATH	ACBP6	physical	24833385
TRXH5_ARATH	TRX5	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
HSDD3_ARATH	AT2G43420	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
PPA3_ARATH	PAP3	physical	24833385
PAM74_ARATH	AT5G59650	physical	24833385
WAK3_ARATH	WAK3	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
TBL18_ARATH	TBL18	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.