BCAS4_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BCAS4_HUMAN
• UniProt AC: Q8TDM0
• Protein Name: Breast carcinoma-amplified sequence 4
• Gene Name: BCAS4
• Organism: Homo sapiens (Human).
• Sequence Length: 211
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MQRTGGGAPRPGRNHGLPGSLRQPDPVALLMLLVDADQPEPMRSGARELALFLTPEPGAEAKEVEETIEGMLLRLEEFCSLADLIRSDTSQILEENIPVLKAKLTEMRGIYAKVDRLEAFVKMVGHHVAFLEADVLQAERDHGAFPQALRRWLGSAGLPSFRNVECSGTIPARCNLRLPGSSDSPASASQVAGITEVTCTGARDVRAAHTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
20	Phosphorylation	RNHGLPGSLRQPDPV CCCCCCCCCCCCCHH	20.59	28060719
101	Ubiquitination	EENIPVLKAKLTEMR HHCCHHHHHHHHHHH	43.65	22817900
101 (in isoform 1)	Ubiquitination	-	43.65	21906983
101 (in isoform 2)	Ubiquitination	-	43.65	21906983
101 (in isoform 3)	Ubiquitination	-	43.65	21906983
103	Ubiquitination	NIPVLKAKLTEMRGI CCHHHHHHHHHHHCC	55.12	22817900
105	Phosphorylation	PVLKAKLTEMRGIYA HHHHHHHHHHHCCHH	27.33	25219547
111	Phosphorylation	LTEMRGIYAKVDRLE HHHHHCCHHHHHHHH	11.82	25219547
155	Phosphorylation	ALRRWLGSAGLPSFR HHHHHHHHCCCCCCC	19.59	-
164	Ubiquitination	GLPSFRNVECSGTIP CCCCCCCEEECCEEC	7.37	27667366
164 (in isoform 3)	Ubiquitination	-	7.37	21906983
165 (in isoform 3)	Phosphorylation	-	26.89	28674419

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BCAS4_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BCAS4_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BCAS4_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PKD2_HUMAN	PKD2	physical	26186194
BL1S6_HUMAN	BLOC1S6	physical	26186194
BL1S2_HUMAN	BLOC1S2	physical	26186194
BL1S5_HUMAN	BLOC1S5	physical	26186194
BL1S1_HUMAN	BLOC1S1	physical	26186194
BORC5_HUMAN	LOH12CR1	physical	26186194
ATG4A_HUMAN	ATG4A	physical	26186194
SNAPN_HUMAN	SNAPIN	physical	26186194
BL1S3_HUMAN	BLOC1S3	physical	26186194
SRCN1_HUMAN	SRCIN1	physical	26186194
SRCN1_HUMAN	SRCIN1	physical	28514442
BL1S5_HUMAN	BLOC1S5	physical	28514442
BL1S6_HUMAN	BLOC1S6	physical	28514442
BL1S3_HUMAN	BLOC1S3	physical	28514442
BL1S1_HUMAN	BLOC1S1	physical	28514442
BORC5_HUMAN	LOH12CR1	physical	28514442
SNAPN_HUMAN	SNAPIN	physical	28514442
BL1S2_HUMAN	BLOC1S2	physical	28514442
PKD2_HUMAN	PKD2	physical	28514442
ATG4A_HUMAN	ATG4A	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.