| UniProt ID | ATPF2_HUMAN | |
|---|---|---|
| UniProt AC | Q8N5M1 | |
| Protein Name | ATP synthase mitochondrial F1 complex assembly factor 2 | |
| Gene Name | ATPAF2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 289 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).. | |
| Protein Sequence | MWRSCLRLRDGGRRLLNRPAGGPSASMSPGPTIPSPARAYAPPTERKRFYQNVSITQGEGGFEINLDHRKLKTPQAKLFTVPSEALAIAVATEWDSQQDTIKYYTMHLTTLCNTSLDNPTQRNKDQLIRAAVKFLDTDTICYRVEEPETLVELQRNEWDPIIEWAEKRYGVEISSSTSIMGPSIPAKTREVLVSHLASYNTWALQGIEFVAAQLKSMVLTLGLIDLRLTVEQAVLLSRLEEEYQIQKWGNIEWAHDYELQELRARTAAGTLFIHLCSESTTVKHKLLKE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Phosphorylation | ----MWRSCLRLRDG ----CCCCCEEECCC | 11.29 | 24719451 | |
| 133 | Succinylation | QLIRAAVKFLDTDTI HHHHHHHHHHCCCCE | 35.17 | - | |
| 133 | Succinylation | QLIRAAVKFLDTDTI HHHHHHHHHHCCCCE | 35.17 | - | |
| 133 | Acetylation | QLIRAAVKFLDTDTI HHHHHHHHHHCCCCE | 35.17 | 25953088 | |
| 183 | Phosphorylation | STSIMGPSIPAKTRE CCCCCCCCCCCCHHH | 35.16 | - | |
| 243 | Phosphorylation | LSRLEEEYQIQKWGN HHHHHHHHHHHHHCC | 17.75 | - | |
| 266 | Phosphorylation | LQELRARTAAGTLFI HHHHHHHHHHCCHHE | 21.63 | 24719451 | |
| 270 | Phosphorylation | RARTAAGTLFIHLCS HHHHHHCCHHEECCC | 17.48 | 24719451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ATPF2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ATPF2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ATPF2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| A4_HUMAN | APP | physical | 21832049 | |
| K1C40_HUMAN | KRT40 | physical | 25416956 | |
| SPG21_HUMAN | SPG21 | physical | 28514442 | |
| FMC1_HUMAN | C7orf55 | physical | 28514442 | |
| ACPM_HUMAN | NDUFAB1 | physical | 28514442 | |
| KLH22_HUMAN | KLHL22 | physical | 28514442 | |
| DNLZ_HUMAN | DNLZ | physical | 28514442 | |
| CLPX_HUMAN | CLPX | physical | 28514442 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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