| UniProt ID | ARN2_YEAST | |
|---|---|---|
| UniProt AC | P38724 | |
| Protein Name | Siderophore iron transporter ARN2 | |
| Gene Name | ARN2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 620 | |
| Subcellular Localization |
Endosome membrane Multi-pass membrane protein. |
|
| Protein Description | Involved in the transport of siderophore triacestylfusarinine C and so has a role in iron homeostasis.. | |
| Protein Sequence | MIEVPEDNRSSQTKRKNTEKNCNELMVDEKMDDDSSPRDEMKDKLKGTKSLIIRKSELMAKKYDTWQLKAIFLFSAFICTFAYGLDSSIRGTYMTYAMNSYSAHSLISTVSVIVLMISAVSQVIFGGLSDIFGRLTLFLVSIVLYIVGTIIQSQAYDVQRYAAGAVFYYVGLVGVMLQVVLMLSDNSSLKWRLFYTLIPSWPSIITTWVSGSVVEAANPLENWSWNIAMWAFIFPLCCIPLILCMLHMRWKVRNDVEWKELQDEKSYYQTHGLVQMLVQLFWKLDVVGVLLFTAGVGCILVPLTLAGGVSTNWRNSKIIGPFVLGFVLVPGFIYWESRLALVPFAPFKLLKDRGVWAPLGIMFFICFVYQMAAGYLYTILVVAVDESASSATRIINLYSFVTAVVAPFLGLIVTRSSRLKSYIIFGGSLYFITMGLFYRYRSGQDADGGIIAGMVIWGLSSCLFDYPTIVSIQSVTSHENMATVTALNYTVFRIGGAVAAAISGAIWTQSLYPKLLHYMGDADLATAAYGSPLTFILSNPWGTPVRSAMVEAYRHVQKYEVIVALVFSAPMFLLTFCVRDPRLTEDFAQKLPDREYVQTKEDDPINDWIAKRFAKALGRS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 10 | Phosphorylation | EVPEDNRSSQTKRKN CCCCCCCCCHHCCCC | 32.81 | 21440633 | |
| 184 | Phosphorylation | LQVVLMLSDNSSLKW HHHHHHHCCCCCCCH | 22.30 | 28889911 | |
| 187 | Phosphorylation | VLMLSDNSSLKWRLF HHHHCCCCCCCHHHH | 41.88 | 28889911 | |
| 188 | Phosphorylation | LMLSDNSSLKWRLFY HHHCCCCCCCHHHHH | 39.98 | 28889911 | |
| 590 | Ubiquitination | LTEDFAQKLPDREYV CCHHHHHHCCCHHHC | 59.57 | 24961812 | |
| 600 | Ubiquitination | DREYVQTKEDDPIND CHHHCCCCCCCCHHH | 41.89 | 24961812 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ARN2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ARN2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ARN2_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ATG15_YEAST | ATG15 | genetic | 20093466 | |
| SSD1_YEAST | SSD1 | genetic | 20093466 | |
| GMC1_YEAST | GMC1 | genetic | 20093466 | |
| AVT6_YEAST | AVT6 | genetic | 20093466 | |
| RTR1_YEAST | RTR1 | genetic | 20093466 | |
| ELP1_YEAST | IKI3 | genetic | 20093466 | |
| MRX11_YEAST | YPL041C | genetic | 20093466 | |
| BRO1_YEAST | BRO1 | genetic | 20526336 | |
| LCB5_YEAST | LCB5 | genetic | 20526336 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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