| UniProt ID | UNG_SCHPO | |
|---|---|---|
| UniProt AC | O74834 | |
| Protein Name | Uracil-DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_03166} | |
| Gene Name | ung1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 322 | |
| Subcellular Localization | Mitochondrion . Nucleus . | |
| Protein Description | Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.. | |
| Protein Sequence | MTVLNTTDKRKADDTVNKLDGKLKQPRLDNFFKTNTSSPALKDTQVLDNKENNSVSKFNKEKWAENLTPAQRKLLQLEIDTLESSWFDALKDEFLKPYFLNLKEFLMKEWQSQRVFPPKEDIYSWSHHTPLHKTKVILLGQDPYHNIGQAHGLCFSVRPGIPCPPSLVNIYKAIKIDYPDFVIPKTGYLVPWADQGILMLNASLTVRAHQAASHSGKGWETFTSAVLQVALNRNRKGLVILAWGTPAAKRLQGLPLKAHYVLRSVHPSPLSAHRGFFECHHFKKTNEWLEEQYGPEKCINWSAVSEQKAKIKSSELESSSTE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 56 | Phosphorylation | NKENNSVSKFNKEKW CCCCCCHHHCCHHHH | 31.20 | 25720772 | |
| 319 | Phosphorylation | KSSELESSSTE---- HHHHHCCCCCC---- | 31.72 | 25720772 | |
| 320 | Phosphorylation | SSELESSSTE----- HHHHCCCCCC----- | 45.92 | 25720772 | |
| 321 | Phosphorylation | SELESSSTE------ HHHCCCCCC------ | 47.89 | 25720772 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UNG_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UNG_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UNG_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PCNA_SCHPO | pcn1 | physical | 22308326 | |
| RYH1_SCHPO | ryh1 | genetic | 22681890 | |
| YIP5_SCHPO | SPAC227.06 | genetic | 22681890 | |
| SPO4_SCHPO | spo4 | genetic | 22681890 | |
| YI41_SCHPO | SPBCPT2R1.01c | genetic | 22681890 | |
| YP41_SCHPO | SPBCPT2R1.01c | genetic | 22681890 | |
| GET1_SCHPO | get1 | genetic | 22681890 | |
| YDA4_SCHPO | SPAC1F12.04c | genetic | 22681890 | |
| SCS7_SCHPO | scs7 | genetic | 22681890 | |
| SGT2_SCHPO | SPAC1142.02c | genetic | 22681890 | |
| SHR3_SCHPO | psh3 | genetic | 22681890 | |
| RGA3_SCHPO | rga3 | genetic | 22681890 | |
| YG0C_SCHPO | SPBC1604.12 | genetic | 22681890 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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