TPR4_ARATH - dbPTM
TPR4_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TPR4_ARATH
UniProt AC Q27GK7
Protein Name Topless-related protein 4
Gene Name TPR4
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1135
Subcellular Localization Nucleus.
Protein Description Transcriptional corepressor. Negative regulator of jasmonate responses (By similarity)..
Protein Sequence MSSLSRELVFLILQFLDEEKFKDTVHRLEKESGFFFNMRYFEDSVTAGEWDDVEKYLSGFTKVDDNRYSMKIFFEIRKQKYLEALDKKDHAKAVDILVKELKVFSTFNEELFKEITMLLTLTNFRENEQLSKYGDTKSARGIMLGELKKLIEANPLFRDKLQFPSLKNSRLRTLINQSLNWQHQLCKNPRPNPDIKTLFVDHTCGHPNGAHTPSPTTNHLMGSVPKVGGFPPLGAHGPFQPTPAPLTTSLAGWMPNPSVQHPTVSAGPIGLGAPNSAVSMLKRERPRSPPTNSLSMDYQTADSESVLKRPRPFGISDGVNNLPVNVLPVTYPGQSHAHATYSTDDLPKNVSRILSQGSAIKSMDFHPVQQTMLLVGTNLGDIAIWEVGSREKLVSRSFKVWDLATCTVNLQASLASEYTAAVNRVVWSPDGGLLGVAYSKHIVHIYSYHGGEDLRNHLEIDAHAGNVNDLAFSQPNQQLCVVTCGEDKTIKVWDAVTGNKLHTFEGHEAPVYSVCPHQKENIQFIFSTAVDGKIKAWLYDNMGSRVDYDAPGRSCTSMAYCADGTRLFSCGTSKEGESFIVEWNESEGAVKRTYLGLGKRSVGVVQFDTMKNKFLVAGDEFQVKFWDMDSVDLLSSTAAEGGLPSSPCLRINKEGTLLAVSTTDNGIKILANAEGSRILHSMANRGLDSSRAPPGSVAKGPIVGTFGTPNSSTGMSLSMGERSGPVASVTGLNGDNRSLPDVKPRIADDAEKSKTWKLTEISERSQLRTLRLPDTLLPARVVKLIYTNSGGAILALAENAAHKLWKWQKSERNLLGKANSNVPPQLWQPSSGVLMTNDTREGNKEDVVPCFALSKNDSYVMSASGGKISLFNMMTFKTMTTFMAPPPAATSLAFHPQDNNIIAIGMDDSSIQIYNVRVDEVKSKLKGHQKRVTGLAFSNVLNVLVSSGADSQLCVWSMDGWEKQASKQIQIPSGHSPNPLAHTRVQFHQDQIHVLVVHASQLAIYEAPKLENMKQWIPKESSGSVTDAVYSCDSQSIYAAFDDGSVSILTATTLQLKCRIGPNSYLPSNPSSRVYPATVAAHPSEPNQFAVGLTDGGVHVIEPPGPEGKWGISAPPENGAGPSVSSAPGSDQQPR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
133PhosphorylationENEQLSKYGDTKSAR
CHHHHHHHCCCHHHH		19.5019880383
214PhosphorylationPNGAHTPSPTTNHLM
CCCCCCCCCCCCCCC		35.71-
288PhosphorylationLKRERPRSPPTNSLS
HHHCCCCCCCCCCCC		37.6023776212
291PhosphorylationERPRSPPTNSLSMDY
CCCCCCCCCCCCCCC		40.6023776212
293PhosphorylationPRSPPTNSLSMDYQT
CCCCCCCCCCCCCCC		25.0523776212
295PhosphorylationSPPTNSLSMDYQTAD
CCCCCCCCCCCCCCC		14.9330407730
298PhosphorylationTNSLSMDYQTADSES
CCCCCCCCCCCCCHH		10.1030407730
723PhosphorylationSLSMGERSGPVASVT
EECCCCCCCCEEEEE		43.0530407730
728PhosphorylationERSGPVASVTGLNGD
CCCCCEEEEECCCCC		22.0525561503
730PhosphorylationSGPVASVTGLNGDNR
CCCEEEEECCCCCCC		33.1925561503
738PhosphorylationGLNGDNRSLPDVKPR
CCCCCCCCCCCCCCC		50.9725561503
1113PhosphorylationPEGKWGISAPPENGA
CCCCCCCCCCCCCCC		30.6830407730
1123PhosphorylationPENGAGPSVSSAPGS
CCCCCCCCCCCCCCC		33.4430407730
1125PhosphorylationNGAGPSVSSAPGSDQ
CCCCCCCCCCCCCCC		25.7230407730
1126PhosphorylationGAGPSVSSAPGSDQQ
CCCCCCCCCCCCCCC		36.0130407730
1130PhosphorylationSVSSAPGSDQQPR--
CCCCCCCCCCCCC--		31.0530407730
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TPR4_ARATH !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TPR4_ARATH !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TPR4_ARATH !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
LBD41_ARATHLBD41physical
22065421
LBD37_ARATHLBD37physical
22065421
RVE7_ARATHEPR1physical
22065421
RAVL1_ARATHTEM1physical
22065421
HSFB1_ARATHHSF4physical
22065421
ZAT10_ARATHSTZphysical
22065421
FRS3_ARATHFRS3physical
22065421
JMJ18_ARATHAT1G30810physical
22065421
TI11B_ARATHJAZ6physical
22065421
ARFB_ARATHARF2physical
22065421
ARFI_ARATHARF9physical
22065421
ARFR_ARATHARF18physical
22065421
TPR1_ARATHTPR1physical
22065421
RAP27_ARATHRAP2.7physical
22065421
IAA10_ARATHIAA10physical
22065421
IAA2_ARATHIAA2physical
22065421
ARFQ_ARATHARF17physical
22065421
TOE2_ARATHTOE2physical
22065421
BZIP9_ARATHBZIP9physical
22065421
RAV1_ARATHRAV1physical
22065421
SPL1_ARATHSPL1physical
22065421
AP2_ARATHAP2physical
22065421
IAA19_ARATHIAA19physical
22065421
HFB2B_ARATHAT-HSFB2Bphysical
22065421
RAVL3_ARATHAT1G51120physical
22065421
TCP8_ARATHAT1G58100physical
22065421
MYB98_ARATHMYB98physical
22065421
BZR1_ARATHBZR1physical
24938363
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TPR4_ARATH

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Related Literatures of Post-Translational Modification

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