dbPTM

TMM92_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TMM92_HUMAN
UniProt AC	Q6UXU6
Protein Name	Transmembrane protein 92
Gene Name	TMEM92
Organism	Homo sapiens (Human).
Sequence Length	159
Subcellular Localization	Membrane Single-pass type I membrane protein .
Protein Description
Protein Sequence	MSQAWVPGLAPTLLFSLLAGPQKIAAKCGLILACPKGFKCCGDSCCQENELFPGPVRIFVIIFLVILSVFCICGLAKCFCRNCREPEPDSPVDCRGPLELPSIIPPERVRVSLSAPPPPYSEVILKPSLGPTPTEPPPPYSFRPEEYTGDQRGIDNPAF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
102	Phosphorylation	RGPLELPSIIPPERV CCCCCCCCCCCHHHE	45.86	27050516
126	Ubiquitination	PYSEVILKPSLGPTP CCCEEEECCCCCCCC	22.80	33845483

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TMM92_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TMM92_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TMM92_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WWOX_HUMAN	WWOX	physical	26186194
NEDD4_HUMAN	NEDD4	physical	26186194
ITCH_HUMAN	ITCH	physical	26186194
NED4L_HUMAN	NEDD4L	physical	26186194
POMT2_HUMAN	POMT2	physical	26186194
POMT1_HUMAN	POMT1	physical	26186194
NFIP1_HUMAN	NDFIP1	physical	26186194
HBB_HUMAN	HBB	physical	26186194
CUED1_HUMAN	CUEDC1	physical	26186194
CNEP1_HUMAN	CTDNEP1	physical	26186194
WWOX_HUMAN	WWOX	physical	28514442
NED4L_HUMAN	NEDD4L	physical	28514442
NEDD4_HUMAN	NEDD4	physical	28514442
POMT2_HUMAN	POMT2	physical	28514442
HBB_HUMAN	HBB	physical	28514442
CUED1_HUMAN	CUEDC1	physical	28514442
ITCH_HUMAN	ITCH	physical	28514442
POMT1_HUMAN	POMT1	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TMM92_HUMAN

Related Literatures of Post-Translational Modification