TAL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAL2_HUMAN
• UniProt AC: Q16559
• Protein Name: T-cell acute lymphocytic leukemia protein 2
• Gene Name: TAL2
• Organism: Homo sapiens (Human).
• Sequence Length: 108
• Protein Sequence: MTRKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVLGEQSLQQTGVAAQGNILGLFPQGPHLPGLEDRTLLENYQVPSPGPSHHIP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Acetylation	SAFAKLRKLIPTHPP HHHHHHHHHCCCCCC	62.29	30592835
31	Phosphorylation	KLRKLIPTHPPDKKL HHHHHCCCCCCCCCC	39.77	-
36	Acetylation	IPTHPPDKKLSKNET CCCCCCCCCCCHHHH	62.48	30592839
91	Phosphorylation	LPGLEDRTLLENYQV CCCCCCCCHHHHCCC	48.28	24719451
100	Phosphorylation	LENYQVPSPGPSHHI HHHCCCCCCCCCCCC	43.57	8152805

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
100	S	Phosphorylation	Kinase	MAPK3	P27361	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAL2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RBTN1_HUMAN	LMO1	physical	7957052
RBTN2_HUMAN	LMO2	physical	7957052
HTF4_HUMAN	TCF12	physical	20211142
MTG8R_HUMAN	CBFA2T2	physical	20211142
PHS2_HUMAN	PCBD2	physical	20211142
ITF2_HUMAN	TCF4	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.