dbPTM

SWET5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SWET5_ARATH
UniProt AC	Q9FM10
Protein Name	Bidirectional sugar transporter SWEET5 {ECO:0000303\|PubMed:21107422}
Gene Name	SWEET5 {ECO:0000303\|PubMed:21107422}
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	240
Subcellular Localization	Cell membrane Multi-pass membrane protein .
Protein Description	Mediates both low-affinity uptake and efflux of sugar across the plasma membrane (By similarity). May play roles in nurturing the male gametophyte. [PubMed: 25988582]
Protein Sequence	MTDPHTARTIVGIVGNVISFGLFCAPIPTMVKIWKMKSVSEFKPDPYVATVLNCMMWTFYGLPFVQPDSLLVITINGTGLFMELVYVTIFFVFATSPVRRKITIAMVIEVIFMAVVIFCTMYFLHTTKQRSMLIGILCIVFNVIMYAAPLTVMKLVIKTKSVKYMPFFLSLANFMNGVVWVIYACLKFDPYILIPNGLGSLSGIIQLIIYITYYKTTNWNDDDEDKEKRYSNAGIELGQA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
230	Phosphorylation	DEDKEKRYSNAGIEL CHHHHHHHHHCCCCC	19.83	22631563
231	Phosphorylation	EDKEKRYSNAGIELG HHHHHHHHHCCCCCC	25.00	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SWET5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SWET5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SWET5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SWET5_ARATH	AtVEX1	physical	24027245
PIP15_ARATH	PIP1;5	physical	24833385
HHP2_ARATH	HHP2	physical	24833385
HHP4_ARATH	HHP4	physical	24833385
MHX_ARATH	MHX	physical	24833385
UBC34_ARATH	UBC34	physical	24833385
FACE2_ARATH	FACE2	physical	24833385
AB12I_ARATH	AT3G21580	physical	24833385
CNIH1_ARATH	AT3G12180	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
RPKL_ARATH	AT4G34220	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385
BET12_ARATH	ATBET12	physical	24833385
MMGT_ARATH	AT5G03345	physical	24833385

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SWET5_ARATH

Related Literatures of Post-Translational Modification