| UniProt ID | STRP1_MOUSE | |
|---|---|---|
| UniProt AC | Q8C079 | |
| Protein Name | Striatin-interacting protein 1 | |
| Gene Name | Strip1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 837 | |
| Subcellular Localization | Cytoplasm. Enriched on the plasma membrane.. | |
| Protein Description | Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape (By similarity).. | |
| Protein Sequence | MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVSDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDSSLEGEAFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MEPAAAGP -------CCCCCCCC | - | ||
| 59 | Phosphorylation | NRNQRKDSEGYSESP CCCCCCCCCCCCCCC | 25521595 | ||
| 62 | Phosphorylation | QRKDSEGYSESPDLE CCCCCCCCCCCCCCC | 25521595 | ||
| 63 | Phosphorylation | RKDSEGYSESPDLEF CCCCCCCCCCCCCCC | 25521595 | ||
| 65 | Phosphorylation | DSEGYSESPDLEFEY CCCCCCCCCCCCCEE | 25619855 | ||
| 209 (in isoform 4) | Phosphorylation | - | 19144319 | ||
| 335 | Phosphorylation | IRNMRAASPPASASD HHHHHHCCCCCCHHH | 24925903 | ||
| 339 | Phosphorylation | RAASPPASASDLIEQ HHCCCCCCHHHHHHH | 25521595 | ||
| 341 | Phosphorylation | ASPPASASDLIEQQQ CCCCCCHHHHHHHHH | 24925903 | ||
| 389 | Phosphorylation | EEENDDDSSLEGEAF HHHCCCCCCCCCCCC | 25338131 | ||
| 390 | Phosphorylation | EENDDDSSLEGEAFP HHCCCCCCCCCCCCC | 25338131 | ||
| 469 | Phosphorylation | PIHESIKTLKQHKYT CHHHHHHHHHHCCCC | - | ||
| 536 | Ubiquitination | LAAAPTSKAKTDSIN HHHCCCCCCCCCCCH | - | ||
| 538 | Ubiquitination | AAPTSKAKTDSINIL HCCCCCCCCCCCHHH | - | ||
| 555 | Phosphorylation | VLPEEMPTTVLQSMK CCCCCCCHHHHHHCC | 26643407 | ||
| 556 | Phosphorylation | LPEEMPTTVLQSMKL CCCCCCHHHHHHCCC | 26643407 | ||
| 560 | Phosphorylation | MPTTVLQSMKLGVDV CCHHHHHHCCCCCCC | 26643407 | ||
| 742 | Ubiquitination | TMSAIYQKVRHRLND HHHHHHHHHHHHCCC | - | ||
| 788 | Phosphorylation | RRYDRTHSNPDFLPV HHCCCCCCCCCCCCH | - | ||
| 831 | Phosphorylation | EVFSKPISWEELLQ- HHHCCCCCHHHHHC- | 17203969 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of STRP1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of STRP1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of STRP1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PP2AA_HUMAN | PPP2CA | physical | 26496610 | |
| 2AAA_HUMAN | PPP2R1A | physical | 26496610 | |
| 2AAB_HUMAN | PPP2R1B | physical | 26496610 | |
| STRN_HUMAN | STRN | physical | 26496610 | |
| SLMAP_HUMAN | SLMAP | physical | 26496610 | |
| STK24_HUMAN | STK24 | physical | 26496610 | |
| PHOCN_HUMAN | MOB4 | physical | 26496610 | |
| INT7_HUMAN | INTS7 | physical | 26496610 | |
| STRN4_HUMAN | STRN4 | physical | 26496610 | |
| STRN3_HUMAN | STRN3 | physical | 26496610 | |
| VATH_HUMAN | ATP6V1H | physical | 26496610 | |
| DC2L1_HUMAN | DYNC2LI1 | physical | 26496610 | |
| CT2NL_HUMAN | CTTNBP2NL | physical | 26496610 | |
| SIKE1_HUMAN | SIKE1 | physical | 26496610 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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