| UniProt ID | SMAP1_MOUSE | |
|---|---|---|
| UniProt AC | Q91VZ6 | |
| Protein Name | Stromal membrane-associated protein 1 | |
| Gene Name | Smap1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 440 | |
| Subcellular Localization |
Cell membrane Peripheral membrane protein Cytoplasmic side . |
|
| Protein Description | GTPase activating protein that acts on ARF6. Plays a role in clathrin-dependent endocytosis. May play a role in erythropoiesis.. | |
| Protein Sequence | MATRSCREKAQKLNEQHQLILSKLLREEDNKYCADCEAKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTPEQIQCMQDMGNTKARLLYEANLPENFRRPQTDQAVEFFIRDKYEKKKYYDKNAIAITNKEKEKKKDEKKREKEPEKPAKPLTTEKLPKKEEQQLEPKKSTSPKNAAEPTIDLLGLDGPAEAPVTNGNPATAPALSDDLDIFGPMISNPLPAAVMPPAQGTASVPAPATLSTVTSGDLDLFTEQTTKSEEVAKKQLSKDSILSLYGTGAQQSTPGVFMGPTNIPFTSQAPTAFQGFPSMGVPVPAAPGLIGNMMGQNTGMMVGMPMHNGFMGNAQTGVMPLPQNVVGPQGGMVGQMGAPQSKFGLPQAQQPQWNLSQMNQQMAAMNLSSANASAGFGQPPSTTAGWSGSSSGQTLSTQLWK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 31 | Acetylation | LLREEDNKYCADCEA HHHHHHCCEECCHHC | 54.77 | 22826441 | |
| 32 | Phosphorylation | LREEDNKYCADCEAK HHHHHCCEECCHHCC | 10.10 | - | |
| 179 | Phosphorylation | QQLEPKKSTSPKNAA HHCCCCCCCCCCCCC | 40.00 | 30352176 | |
| 180 | Phosphorylation | QLEPKKSTSPKNAAE HCCCCCCCCCCCCCC | 58.91 | 25338131 | |
| 181 | Phosphorylation | LEPKKSTSPKNAAEP CCCCCCCCCCCCCCC | 40.75 | 19367708 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SMAP1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SMAP1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SMAP1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CLCA_HUMAN | CLTA | physical | 26496610 | |
| CLCB_HUMAN | CLTB | physical | 26496610 | |
| CLH1_HUMAN | CLTC | physical | 26496610 | |
| STOM_HUMAN | STOM | physical | 26496610 | |
| PDE4D_HUMAN | PDE4D | physical | 26496610 | |
| SEC62_HUMAN | SEC62 | physical | 26496610 | |
| EPN4_HUMAN | CLINT1 | physical | 26496610 | |
| RSRC1_HUMAN | RSRC1 | physical | 26496610 | |
| GTSE1_HUMAN | GTSE1 | physical | 26496610 | |
| KDIS_HUMAN | KIDINS220 | physical | 26496610 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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