SET1B_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SET1B_HUMAN
• UniProt AC: Q9UPS6
• Protein Name: Histone-lysine N-methyltransferase SETD1B
• Gene Name: SETD1B
• Organism: Homo sapiens (Human).
• Sequence Length: 1966
• Subcellular Localization: Nucleus speckle . Chromosome . Localizes to a largely non-overlapping set of euchromatic nuclear speckles with SETD1A, suggesting that SETD1A and SET1B each bind to a unique set of target genes.
• Protein Description: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase (HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overlapping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro..
• Protein Sequence: MENSHPPHHHHQQPPPQPGPSGERRNHHWRSYKLMIDPALKKGHHKLYRYDGQHFSLAMSSNRPVEIVEDPRVVGIWTKNKELELSVPKFKIDEFYVGPVPPKQVTFAKLNDNIRENFLRDMCKKYGEVEEVEILYNPKTKKHLGIAKVVFATVRGAKDAVQHLHSTSVMGNIIHVELDTKGETRMRFYELLVTGRYTPQTLPVGELDAVSPIVNETLQLSDALKRLKDGGLSAGCGSGSSSVTPNSGGTPFSQDTAYSSCRLDTPNSYGQGTPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPAVTFKARRHESKFTDAYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMVEVVAFRAFDEWWDKKERMAKASLTPVKSGEHKDEDRPKPKDRIASCLLESWGKGEGLGYEGLGLGIGLRGAIRLPSFKVKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEKESLSASSSSSASSSSGSSTTSPSSSASDKEEEQESTEEEEEAEEEEEEEVPRSQLSSSSTSSTSDKDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQPLFRPRSEFEEMTILYDIWNGGIDEEDIRFLCVTYERLLQQDNGMDWLNDTLWVYHPSTSLSSAKKKKRDDGIREHVTGCARSEGFYTIDKKDKLRYLNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLKFRKKKLKFCKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNEEITYDYKFPIEDVKIPCLCGSENCRGTLN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
31	Phosphorylation	RRNHHWRSYKLMIDP CCCCCHHHEEEECCH	22.79	28270605
32	Phosphorylation	RNHHWRSYKLMIDPA CCCCHHHEEEECCHH	10.28	28270605
41	"N6,N6-dimethyllysine"	LMIDPALKKGHHKLY EECCHHHHHCCCEEE	59.83	-
41	Methylation	LMIDPALKKGHHKLY EECCHHHHHCCCEEE	59.83	-
48	Phosphorylation	KKGHHKLYRYDGQHF HHCCCEEEEECCCEE	16.36	25278378
50	Phosphorylation	GHHKLYRYDGQHFSL CCCEEEEECCCEEEE	15.74	24719451
56	Phosphorylation	RYDGQHFSLAMSSNR EECCCEEEEEECCCC	17.06	25278378
60	Phosphorylation	QHFSLAMSSNRPVEI CEEEEEECCCCCEEE	20.89	25278378
61	Phosphorylation	HFSLAMSSNRPVEIV EEEEEECCCCCEEEC	24.63	25278378
78	Phosphorylation	PRVVGIWTKNKELEL CCEEEEEECCCEEEE	23.87	-
86	Phosphorylation	KNKELELSVPKFKID CCCEEEEECCCCCCC	27.31	24719451
96	Phosphorylation	KFKIDEFYVGPVPPK CCCCCEEEECCCCHH	11.49	-
126	Phosphorylation	LRDMCKKYGEVEEVE HHHHHHHHCCEEEEE	12.19	-
194	Phosphorylation	RFYELLVTGRYTPQT EEEEHHHHCCCCCCC	18.86	24719451
197	Phosphorylation	ELLVTGRYTPQTLPV EHHHHCCCCCCCCCC	24.90	27732954
198	Phosphorylation	LLVTGRYTPQTLPVG HHHHCCCCCCCCCCC	13.94	27732954
201	Phosphorylation	TGRYTPQTLPVGELD HCCCCCCCCCCCCCC	33.94	27732954
211	Phosphorylation	VGELDAVSPIVNETL CCCCCCCCHHHHHHH	15.61	30278072
217	Phosphorylation	VSPIVNETLQLSDAL CCHHHHHHHHHHHHH	18.01	26657352
221	Phosphorylation	VNETLQLSDALKRLK HHHHHHHHHHHHHHH	14.10	28450419
238	Phosphorylation	GLSAGCGSGSSSVTP CCCCCCCCCCCCCCC	39.31	28348404
242	Phosphorylation	GCGSGSSSVTPNSGG CCCCCCCCCCCCCCC	31.54	24719451
244	Phosphorylation	GSGSSSVTPNSGGTP CCCCCCCCCCCCCCC	20.78	23401153
265	Phosphorylation	YSSCRLDTPNSYGQG CCCCCCCCCCCCCCC	29.03	25159151
273	Phosphorylation	PNSYGQGTPLTPRLG CCCCCCCCCCCCCCC	13.77	29978859
276	Phosphorylation	YGQGTPLTPRLGTPF CCCCCCCCCCCCCCC	13.94	29978859
278	Methylation	QGTPLTPRLGTPFSQ CCCCCCCCCCCCCCC	40.28	81453683
291	Phosphorylation	SQDSSYSSRQPTPSY CCCCCCCCCCCCCHH	27.05	-
295	Phosphorylation	SYSSRQPTPSYLFSQ CCCCCCCCCHHHCCC	19.27	21815630
309	Methylation	QDPAVTFKARRHESK CCCCCEEEECCCHHH	31.45	115981445
360	Phosphorylation	PFGAVGGTGGSSGPP CCCCCCCCCCCCCCC	32.23	28555341
363	Phosphorylation	AVGGTGGSSGPPFKA CCCCCCCCCCCCCCC	33.20	28555341
375	Phosphorylation	FKAQPQDSATFAHTP CCCCCCCCCCCCCCC	24.78	30266825
377	Phosphorylation	AQPQDSATFAHTPPP CCCCCCCCCCCCCCC	25.88	30266825
381	Phosphorylation	DSATFAHTPPPAQAT CCCCCCCCCCCHHCC	33.78	30266825
388	Phosphorylation	TPPPAQATPAPGFKS CCCCHHCCCCCCCCC	14.11	30266825
394	Methylation	ATPAPGFKSAFSPYQ CCCCCCCCCCCCCCC	46.95	115981451
395	Phosphorylation	TPAPGFKSAFSPYQT CCCCCCCCCCCCCCC	32.08	25849741
398	Phosphorylation	PGFKSAFSPYQTPVA CCCCCCCCCCCCCCC	23.55	25849741
400	Phosphorylation	FKSAFSPYQTPVAHF CCCCCCCCCCCCCCC	24.66	28450419
402	Phosphorylation	SAFSPYQTPVAHFPP CCCCCCCCCCCCCCC	17.56	25394399
415	Phosphorylation	PPPPEEPTATAAFGA CCCCCCCCCCCCCCC	39.66	24247654
425	Phosphorylation	AAFGARDSGEFRRAP CCCCCCCCCCCCCCC	34.37	26074081
450	Phosphorylation	LAKEKPGTPPGPPPP CCCCCCCCCCCCCCC	34.53	25849741
469	Phosphorylation	MELGGRPTFGWSPEP CCCCCCCCCCCCCCC	33.16	20873877
473	Phosphorylation	GRPTFGWSPEPCDSP CCCCCCCCCCCCCCC	21.55	20873877
479	Phosphorylation	WSPEPCDSPGTPTLE CCCCCCCCCCCCCCC	31.76	20873877
482	Phosphorylation	EPCDSPGTPTLESSP CCCCCCCCCCCCCCC	19.24	20873877
484	Phosphorylation	CDSPGTPTLESSPAG CCCCCCCCCCCCCCC	42.89	20873877
487	Phosphorylation	PGTPTLESSPAGPEK CCCCCCCCCCCCCCC	44.74	20873877
488	Phosphorylation	GTPTLESSPAGPEKP CCCCCCCCCCCCCCC	14.92	20873877
498	Phosphorylation	GPEKPHDSLDSRIEM CCCCCCCCHHHHHHH	30.92	20873877
501	Phosphorylation	KPHDSLDSRIEMLLK CCCCCHHHHHHHHHH	40.21	20873877
787	Phosphorylation	QVLSRLMTGQGACPY HHHHHHHCCCCCCCC	30.83	24043423
794	Phosphorylation	TGQGACPYPPFMAAA CCCCCCCCHHHHHHH	24.34	24043423
806	Phosphorylation	AAAAAAASAGLQFVN HHHHHHHHCCCEECC	20.38	24043423
817	Phosphorylation	QFVNLPPYRGPFSLS EECCCCCCCCCCCCC	26.68	24043423
824	Phosphorylation	YRGPFSLSNSGPGRG CCCCCCCCCCCCCCC	27.96	28450419
826	Phosphorylation	GPFSLSNSGPGRGQH CCCCCCCCCCCCCCC	42.88	28450419
907	Phosphorylation	KERMAKASLTPVKSG HHHHHHHCCCCCCCC	31.88	30266825
909	Phosphorylation	RMAKASLTPVKSGEH HHHHHCCCCCCCCCC	24.44	30266825
913	Phosphorylation	ASLTPVKSGEHKDED HCCCCCCCCCCCCCC	50.04	-
961	Phosphorylation	RGAIRLPSFKVKRKE CCEEECCCCCEECCC	42.14	23917254
972	Phosphorylation	KRKEPPDTTSSGDQK ECCCCCCCCCCCCCC	34.06	-
973	Phosphorylation	RKEPPDTTSSGDQKR CCCCCCCCCCCCCCC	28.42	-
974	Phosphorylation	KEPPDTTSSGDQKRL CCCCCCCCCCCCCCC	34.12	-
975	Phosphorylation	EPPDTTSSGDQKRLR CCCCCCCCCCCCCCC	44.27	-
984	Phosphorylation	DQKRLRPSTSVDEED CCCCCCCCCCCCCCH	27.21	23401153
985	Phosphorylation	QKRLRPSTSVDEEDE CCCCCCCCCCCCCHH	35.14	29255136
986	Phosphorylation	KRLRPSTSVDEEDEE CCCCCCCCCCCCHHH	31.73	29255136
994	Phosphorylation	VDEEDEESERERDRD CCCCHHHHHHHHHHH	39.65	23401153
1005	Phosphorylation	RDRDMADTPCELAKR HHHHHCCCHHHHHHH	21.94	26657352
1031	Phosphorylation	ARPLELDSGGEEDEK CCCCCCCCCCCCCHH	62.41	25850435
1042 (in isoform 2)	Phosphorylation	-	48.65	23879269
1044	Phosphorylation	EKESLSASSSSSASS HHHHCCCCCCCCCCC	57.16	30576142
1047 (in isoform 2)	Phosphorylation	-	40.59	23879269
1059	Phosphorylation	SSGSSTTSPSSSASD CCCCCCCCCCCCCCC	70.71	30576142
1063	Phosphorylation	STTSPSSSASDKEEE CCCCCCCCCCCHHHH	65.60	30576142
1094	Phosphorylation	EVPRSQLSSSSTSST HCCHHHCCCCCCCCC	58.75	27251275
1117	Phosphorylation	DSDDRDESENDDEDT CCCCCCHHCCCHHHH	68.51	20873877
1124	Phosphorylation	SENDDEDTALSEASE HCCCHHHHHHHHHHH	30.81	30108239
1127	Phosphorylation	DDEDTALSEASEKDE CHHHHHHHHHHHHCC	49.88	30108239
1130	Phosphorylation	DTALSEASEKDEGDS HHHHHHHHHHCCCCC	48.74	30108239
1137	Phosphorylation	SEKDEGDSDEEETVS HHHCCCCCCHHHEEE	40.00	25849741
1240	Phosphorylation	EVDIETEAVAPEERP CCCCCEEECCCCCCC	24.21	-
1255	Phosphorylation	SMLDEPPLPVGVEEP CCCCCCCCCCCCCCC	30.41	-
1265	Phosphorylation	GVEEPADSREPPEEP CCCCCCCCCCCCCCC	51.39	-
1275	Phosphorylation	PPEEPGLSQEGAMLL CCCCCCCCCCCCCEE	17.65	30266825
1283	Phosphorylation	QEGAMLLSPEPPAKE CCCCCEECCCCCCCC	42.49	26657352
1292	Phosphorylation	EPPAKEVEARPPLSP CCCCCCCCCCCCCCC	53.36	-
1298	Phosphorylation	VEARPPLSPERAPEH CCCCCCCCCCCCCCC	63.78	30266825
1335	Phosphorylation	PRPPRPPSPPPEPET CCCCCCCCCCCCCCC	31.70	24275569
1347	Phosphorylation	PETTDASHPSVPPEP CCCCCCCCCCCCCCC	47.05	27251275
1382	Phosphorylation	STETVPATPGGEPPL CCCEECCCCCCCCCC	28.31	24719451
1388	Phosphorylation	ATPGGEPPLSGGSSG CCCCCCCCCCCCCCC	32.28	27251275
1390	Phosphorylation	PGGEPPLSGGSSGLS CCCCCCCCCCCCCCC	21.88	28348404
1393	Phosphorylation	EPPLSGGSSGLSLSS CCCCCCCCCCCCCCC	9.07	28348404
1394	Phosphorylation	PPLSGGSSGLSLSSP CCCCCCCCCCCCCCC	51.59	28348404
1397	Phosphorylation	SGGSSGLSLSSPQVP CCCCCCCCCCCCCCC	49.33	28348404
1399	Phosphorylation	GSSGLSLSSPQVPGS CCCCCCCCCCCCCCC	24.95	28348404
1400	Phosphorylation	SSGLSLSSPQVPGSP CCCCCCCCCCCCCCC	9.77	28348404
1406	Phosphorylation	SSPQVPGSPFSYPAP CCCCCCCCCCCCCCC	41.42	28348404
1409	Phosphorylation	QVPGSPFSYPAPSPS CCCCCCCCCCCCCCC	51.51	28348404
1421	Phosphorylation	SPSLSSGGLPRTPGR CCCCCCCCCCCCCCC	24.19	24719451
1425	Phosphorylation	SSGGLPRTPGRDFSF CCCCCCCCCCCCCCC	5.88	25106551
1431	Phosphorylation	RTPGRDFSFTPTFSE CCCCCCCCCCCCCCC	9.05	25106551
1433	Phosphorylation	PGRDFSFTPTFSEPS CCCCCCCCCCCCCCC	10.04	25106551
1435	Phosphorylation	RDFSFTPTFSEPSGP CCCCCCCCCCCCCCC	10.04	28450419
1437	Phosphorylation	FSFTPTFSEPSGPLL CCCCCCCCCCCCCEE	10.04	28450419
1440	O-linked_Glycosylation	TPTFSEPSGPLLLPV CCCCCCCCCCEEEEE	17.41	29351928
1440	Phosphorylation	TPTFSEPSGPLLLPV CCCCCCCCCCEEEEE	17.41	28122231
1452	Phosphorylation	LPVCPLPTGRRDERS EEECCCCCCCCCCCC	29.08	24043423
1464	Phosphorylation	ERSGPLASPVLLETG CCCCCCCCCEECCCC	26.90	27251275
1495	Methylation	AVLRAQARAPTPLPP HHHHHHCCCCCCCCC	38.89	-
1504	Methylation	PTPLPPLLPAPLASC CCCCCCCCCCCHHHC	32.04	-
1515	Phosphorylation	LASCPPPMKRKPGRP HHHCCCCCCCCCCCC	28.27	24719451
1525	Phosphorylation	KPGRPRRSPPSMLSL CCCCCCCCCCCHHCC	48.13	26074081
1528	Phosphorylation	RPRRSPPSMLSLDGP CCCCCCCCHHCCCCC	21.72	26074081
1531	Phosphorylation	RSPPSMLSLDGPLVR CCCCCHHCCCCCCCC	7.94	26074081
1538	Methylation	SLDGPLVRPPAGAAL CCCCCCCCCCCCCCC	27.58	115916509
1547	Methylation	PAGAALGRELLLLPG CCCCCCCCEEEECCC	49.49	115916513
1558	Phosphorylation	LLPGQPQTPVFPSTH ECCCCCCCCCCCCCC	34.76	28450419
1563	Phosphorylation	PQTPVFPSTHDPRTV CCCCCCCCCCCCCEE	16.21	28450419
1564	Phosphorylation	QTPVFPSTHDPRTVT CCCCCCCCCCCCEEE	56.26	28450419
1616	Phosphorylation	LDNQWPSEAIPPGPR CCCCCCCCCCCCCCC	19.80	24719451
1620	Phosphorylation	WPSEAIPPGPRGRDE CCCCCCCCCCCCCHH	32.64	24719451
1632	Phosphorylation	RDEVTEEYMELAKSR CHHHHHHHHHHHHHH	11.54	22144111
1659	Phosphorylation	DLVPPAGSPELSPPQ HCCCCCCCCCCCCCC	27.73	29255136
1663	Phosphorylation	PAGSPELSPPQPLFR CCCCCCCCCCCCCCC	53.85	29255136
1728	Phosphorylation	YHPSTSLSSAKKKKR ECCCCCHHHHHHHHC	43.31	27251275
1729	Phosphorylation	HPSTSLSSAKKKKRD CCCCCHHHHHHHHCC	65.00	-
1749	Phosphorylation	HVTGCARSEGFYTID HCHHCCCCCCEEEEC	34.16	-
1763	Phosphorylation	DKKDKLRYLNSSRAS CHHHCHHHHCCCCCC	28.18	28450419
1764	Phosphorylation	KKDKLRYLNSSRAST HHHCHHHHCCCCCCC	27.14	27251275
1766	Phosphorylation	DKLRYLNSSRASTDE HCHHHHCCCCCCCCC	30.08	28450419
1767	Phosphorylation	KLRYLNSSRASTDEP CHHHHCCCCCCCCCC	25.02	28450419
1770	Phosphorylation	YLNSSRASTDEPPAD HHCCCCCCCCCCCCC	47.05	26657352
1771	Phosphorylation	LNSSRASTDEPPADT HCCCCCCCCCCCCCC	34.19	28450419
1778	Phosphorylation	TDEPPADTQGMSIPA CCCCCCCCCCCCCCC	49.51	23186163
1782	Phosphorylation	PADTQGMSIPAQPHA CCCCCCCCCCCCCCC	48.58	23312004
1790	Acetylation	IPAQPHASTRAGSER CCCCCCCCCCCCCHH	48.48	-
1790	Phosphorylation	IPAQPHASTRAGSER CCCCCCCCCCCCCHH	48.48	23312004
1791	Phosphorylation	PAQPHASTRAGSERR CCCCCCCCCCCCHHH	28.93	23186163
1806	Phosphorylation	SEQRRLLSSFTGSCD HHHHHHHHHHHCCCC	17.64	24719451
1807	Phosphorylation	EQRRLLSSFTGSCDS HHHHHHHHHHCCCCH	35.19	23403867
1809	Phosphorylation	RRLLSSFTGSCDSDL HHHHHHHHCCCCHHH	3.66	23403867
1811	Phosphorylation	LLSSFTGSCDSDLLK HHHHHHCCCCHHHHH	2.81	23403867
1833	Acetylation	KKKLKFCKSHIHDWG HHHHHHHHHHHHCCE	40.55	20167786
1873	Phosphorylation	ADMREKRYEDEGIGS HHHHHHHHCCCCCCC	3.18	22210691
1915	Acetylation	CNPNCYAKVITVESQ CCCCCEEEEEEECCC	25.33	26051181
1918	Phosphorylation	NCYAKVITVESQKKI CCEEEEEEECCCCEE	3.59	28270605
1921	Phosphorylation	AKVITVESQKKIVIY EEEEEECCCCEEEEE	12.08	28270605
1924	Acetylation	ITVESQKKIVIYSKQ EEECCCCEEEEEECC		26051181
1930	Acetylation	KKIVIYSKQHINVNE CEEEEEECCCCCCCC		26051181

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SET1B_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SET1B_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SET1B_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CXXC1_HUMAN	CXXC1	physical	17355966
RBBP5_HUMAN	RBBP5	physical	17355966
WDR5_HUMAN	WDR5	physical	17355966
ASH2L_HUMAN	ASH2L	physical	17998332
RPB1_HUMAN	POLR2A	physical	17998332
WDR82_HUMAN	WDR82	physical	20516061
RBBP5_HUMAN	RBBP5	physical	20516061
WDR5_HUMAN	WDR5	physical	22665483
H32_HUMAN	HIST2H3C	physical	22266653
H31_HUMAN	HIST1H3A	physical	23870121
SET1A_HUMAN	SETD1A	physical	17355966
MVD1_HUMAN	MVD	physical	26496610
RBBP5_HUMAN	RBBP5	physical	26496610
ASH2L_HUMAN	ASH2L	physical	26496610
WDR5_HUMAN	WDR5	physical	26496610
WBP4_HUMAN	WBP4	physical	26496610
ZC3H3_HUMAN	ZC3H3	physical	26496610
CXXC1_HUMAN	CXXC1	physical	26496610
RBM26_HUMAN	RBM26	physical	26496610
DPY30_HUMAN	DPY30	physical	26496610
WDR5_HUMAN	WDR5	physical	27563068
RBBP5_HUMAN	RBBP5	physical	27563068
ASH2L_HUMAN	ASH2L	physical	27563068
CXXC1_HUMAN	CXXC1	physical	27563068
WDR82_HUMAN	WDR82	physical	27563068

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1616 AND SER-1620, ANDMASS SPECTROMETRY.
PubMed: 18669648

"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks.";
Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.;
Cell 127:635-648(2006).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1616 AND SER-1620, ANDMASS SPECTROMETRY.
PubMed: 17081983