UniProt ID | RNG1A_ARATH | |
---|---|---|
UniProt AC | Q9FKW0 | |
Protein Name | Putative E3 ubiquitin-protein ligase RING1a | |
Gene Name | RING1A | |
Organism | Arabidopsis thaliana (Mouse-ear cress). | |
Sequence Length | 522 | |
Subcellular Localization | Nucleus . | |
Protein Description | Putative E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119ub), thereby playing a central role in histone code and gene regulation.; As part of the PRC1-like complex, repress class I KNOX gene expression. PcG PRC1 complex maintains the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility.. | |
Protein Sequence | MSVKNNSFSSAEIPDVADQPRDRFNPEATQDLQEKDETKEEKEGDEEVKHDEAEEDQEVVKPNDAEEDDDGDDAEEDEEEEVEAEEDEEAEEEEEEEEEEEEEEEDSKERSPSSISGDQSEFMEIDLGEIRKDVQCPICLGIIKKTRTVMECLHRFCRECIDKSMRLGNNECPACRKHCASRRSLRDDPKFDALIAALFTNIDSYEEEELAFHEDEMARNKQIQASIAQISQRQSEALVKRRSLGKEAAVLMRSPRIASGSRRRRNSRNMEQQNASEAHEDDDNDDNNNRGRDKDSSSDERGTEVRQKKRRKRSTSRSTQHPSSSGANKNNGNCADNDTEVYRDTKGISPGLVWNPEILAWGRGGTRSNTRHGNNTSGGSSKSVRNARVNKLVEYLRSSVDGSSVELDIHVKLVSLDTKCIPDLPQPYLCCRPTLLVKQLREFVALQIHLKTEEVELLVTRRRVGEDAAIENLPAVTPASAAASKDEMLSLEDNETLSRLKIDFISSHEQHLIIAYRKKQTE | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
7 | Phosphorylation | -MSVKNNSFSSAEIP -CCCCCCCCCCCCCC | 35.58 | 30291188 | |
323 | Phosphorylation | SRSTQHPSSSGANKN CCCCCCCCCCCCCCC | 34.70 | 25561503 | |
324 | Phosphorylation | RSTQHPSSSGANKNN CCCCCCCCCCCCCCC | 36.92 | 25561503 | |
325 | Phosphorylation | STQHPSSSGANKNNG CCCCCCCCCCCCCCC | 46.38 | 25561503 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RNG1A_ARATH !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RNG1A_ARATH !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RNG1A_ARATH !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
ALFL1_ARATH | AL1 | physical | 24465219 | |
ALFL2_ARATH | AL2 | physical | 24465219 | |
ALFL5_ARATH | AL5 | physical | 24465219 | |
ALFL6_ARATH | AL6 | physical | 24465219 | |
ALFL7_ARATH | AL7 | physical | 24465219 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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