RBM18_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RBM18_HUMAN
• UniProt AC: Q96H35
• Protein Name: Probable RNA-binding protein 18
• Gene Name: RBM18
• Organism: Homo sapiens (Human).
• Sequence Length: 190
• Protein Sequence: MEAETKTLPLENASILSEGSLQEGHRLWIGNLDPKITEYHLLKLLQKFGKVKQFDFLFHKSGALEGQPRGYCFVNFETKQEAEQAIQCLNGKLALSKKLVVRWAHAQVKRYDHNKNDKILPISLEPSSSTEPTQSNLSVTAKIKAIEAKLKMMAENPDAEYPAAPVYSYFKPPDKKRTTPYSRTAWKSRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Ubiquitination	ITEYHLLKLLQKFGK HHHHHHHHHHHHHCC	54.21	29967540
130	Phosphorylation	SLEPSSSTEPTQSNL EECCCCCCCCCCCCC	48.18	21712546
133	Phosphorylation	PSSSTEPTQSNLSVT CCCCCCCCCCCCEEH	38.10	21712546
135	Phosphorylation	SSTEPTQSNLSVTAK CCCCCCCCCCEEHHH	42.06	21712546
161	Phosphorylation	AENPDAEYPAAPVYS HHCCCCCCCCCCCCC	10.41	-
167	Phosphorylation	EYPAAPVYSYFKPPD CCCCCCCCCCCCCCC	9.15	21945579
168	Phosphorylation	YPAAPVYSYFKPPDK CCCCCCCCCCCCCCC	25.07	21945579
169	Phosphorylation	PAAPVYSYFKPPDKK CCCCCCCCCCCCCCC	9.64	21945579

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RBM18_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RBM18_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RBM18_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TMM27_HUMAN	TMEM27	physical	21988832
TAP2_HUMAN	TAP2	physical	21988832
ACTA_HUMAN	ACTA2	physical	26186194
GELS_HUMAN	GSN	physical	26186194
TMOD2_HUMAN	TMOD2	physical	26186194
UBR3_HUMAN	UBR3	physical	26186194
RIOX2_HUMAN	MINA	physical	26186194
CAZA2_HUMAN	CAPZA2	physical	26186194
CNRP1_HUMAN	CNRIP1	physical	26186194
RIOX2_HUMAN	MINA	physical	28514442
TMOD2_HUMAN	TMOD2	physical	28514442
GELS_HUMAN	GSN	physical	28514442
CNRP1_HUMAN	CNRIP1	physical	28514442
UBR3_HUMAN	UBR3	physical	28514442
ACTA_HUMAN	ACTA2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.