RAS2_DROME - dbPTM
RAS2_DROME - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAS2_DROME
UniProt AC P04388
Protein Name Ras-like protein 2
Gene Name Ras64B
Organism Drosophila melanogaster (Fruit fly).
Sequence Length 192
Subcellular Localization Cell membrane
Lipid-anchor
Cytoplasmic side .
Protein Description May be involved in endocytic processes and/or other transport pathways mediated by vesicle trafficking. May interact functionally with ROP protein. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity..
Protein Sequence MQMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQIAERPFIEQDYKKKGKRKCCLM
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
46S-palmitoylationEDSYTKQCNIDDVPA
CHHCCCCCCCCCCCC
5.2730735487
120S-palmitoylationMLMVGNKCDLKHQQQ
EEEECCCCCCCCHHH
9.5730735487
147S-palmitoylationLMIPYIECSAKLRVN
CCEEEEEEEEEEECC
3.3030735487
189MethylationKKKGKRKCCLM----
HHCCCCCCCCC----
2.21-
189FarnesylationKKKGKRKCCLM----
HHCCCCCCCCC----
2.21-
189S-palmitoylationKKKGKRKCCLM----
HHCCCCCCCCC----
2.2130735487
190S-palmitoylationKKGKRKCCLM-----
HCCCCCCCCC-----
3.9830735487

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAS2_DROME !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAS2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAS2_DROME !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DECA_DROMEdppgenetic
9056776
SPY_DROMEstygenetic
12932331
GIL_DROMEaosgenetic
12932331
RAS1_DROMERas85Dgenetic
12932331
SPRI_DROMEspriphysical
16054027

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAS2_DROME

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Related Literatures of Post-Translational Modification

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