dbPTM

PYL5_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PYL5_ARATH
UniProt AC	Q9FLB1
Protein Name	Abscisic acid receptor PYL5
Gene Name	PYL5
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	203
Subcellular Localization	Cytoplasm . Nucleus . Cell membrane . Localizes at the plasma membrane in the presence of a CAR protein.
Protein Description	Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) in an ABA-independent manner but more efficiently when activated by ABA. Confers enhanced sensitivity to ABA. [PubMed: 19407143]
Protein Sequence	MRSPVQLQHGSDATNGFHTLQPHDQTDGPIKRVCLTRGMHVPEHVAMHHTHDVGPDQCCSSVVQMIHAPPESVWALVRRFDNPKVYKNFIRQCRIVQGDGLHVGDLREVMVVSGLPAVSSTERLEILDEERHVISFSVVGGDHRLKNYRSVTTLHASDDEGTVVVESYIVDVPPGNTEEETLSFVDTIVRCNLQSLARSTNRQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
86	Phosphorylation	RFDNPKVYKNFIRQC HCCCHHHHHHHHHHC	13.31	22074104

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PYL5_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PYL5_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PYL5_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
P2C77_ARATH	ABI2	physical	21798944
P2C03_ARATH	HAI2	physical	22829320
P2C24_ARATH	HAI3	physical	22829320
P2C16_ARATH	HAB1	physical	22829320
PYL13_ARATH	PYL13	physical	24189045
P2C16_ARATH	HAB1	physical	19407142
P2C37_ARATH	PP2CA	physical	19407142
P2C16_ARATH	HAB1	physical	20729862
P2C56_ARATH	ABI1	physical	20729862
P2C77_ARATH	ABI2	physical	20729862

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PYL5_ARATH

Related Literatures of Post-Translational Modification