| UniProt ID | PS6AA_ARATH | |
|---|---|---|
| UniProt AC | Q9SEI2 | |
| Protein Name | 26S proteasome regulatory subunit 6A homolog A | |
| Gene Name | RPT5A | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 424 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. Plays a essential role in the gametophyte development.. | |
| Protein Sequence | MATPMVEDTSSFEEDQLASMSTEDITRATRLLDNEIRILKEDAQRTNLECDSYKEKIKENQEKIKLNKQLPYLVGNIVEILEMNPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDSLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKERFEKLGVRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFQLAKEKAPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDERIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARARILQIHSRKMNVHPDVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASLNYYA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MATPMVEDT ------CCCCCCCCC | 22.02 | 22223895 | |
| 19 | Phosphorylation | FEEDQLASMSTEDIT CCHHHHHCCCHHHHH | 23.12 | - | |
| 52 | Phosphorylation | RTNLECDSYKEKIKE HHCCCCHHHHHHHHH | 50.16 | 23111157 | |
| 53 | Phosphorylation | TNLECDSYKEKIKEN HCCCCHHHHHHHHHH | 15.20 | 23111157 | |
| 278 | Acetylation | DEIDAIGTKRFDSEV ECCCCCCCCCCCCCC | 16.97 | 20516081 | |
| 279 | Ubiquitination | EIDAIGTKRFDSEVS CCCCCCCCCCCCCCC | 45.94 | 20516081 | |
| 283 | Phosphorylation | IGTKRFDSEVSGDRE CCCCCCCCCCCCCHH | 36.87 | 19880383 | |
| 286 | Phosphorylation | KRFDSEVSGDREVQR CCCCCCCCCCHHHHH | 30.81 | 19880383 | |
| 416 | Ubiquitination | IIQVQAKKKASLNYY EEEEEEECCCCCCCC | 57.50 | 20516081 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PS6AA_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PS6AA_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PS6AA_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PS6AA_ARATH | RPT5A | physical | 9878390 | |
| PSD11_ARATH | ATS9 | physical | 9878390 | |
| ODPA1_ARATH | E1 ALPHA | physical | 24846764 | |
| ODP24_ARATH | LTA2 | physical | 24846764 | |
| RBS1A_ARATH | RBCS1A | physical | 24846764 | |
| CLPP4_ARATH | CLPP4 | physical | 24846764 | |
| FTSH1_ARATH | FTSH1 | physical | 24846764 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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