UniProt ID | PRDM4_HUMAN | |
---|---|---|
UniProt AC | Q9UKN5 | |
Protein Name | PR domain zinc finger protein 4 | |
Gene Name | PRDM4 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 801 | |
Subcellular Localization | Nucleus . | |
Protein Description | May function as a transcription factor involved in cell differentiation.. | |
Protein Sequence | MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
198 | Phosphorylation | AITMENVSRVTSPIS EEEEECCCCCCCCCC | 32.39 | - | |
201 | Phosphorylation | MENVSRVTSPISTDG EECCCCCCCCCCCCC | 27.89 | 29978859 | |
202 | Phosphorylation | ENVSRVTSPISTDGM ECCCCCCCCCCCCCC | 19.85 | 27050516 | |
205 | Phosphorylation | SRVTSPISTDGMAEE CCCCCCCCCCCCCCE | 24.67 | 29978859 | |
206 | Phosphorylation | RVTSPISTDGMAEEL CCCCCCCCCCCCCEE | 36.97 | 22115753 | |
412 | Ubiquitination | RARLSLPKQLVLRQS HHCCCCCHHHHHHHH | 62.65 | 21890473 | |
447 | Phosphorylation | GPLIGQQSHSMEVAE HHHCCCCCCCCHHHH | 15.05 | 28509920 | |
593 | Phosphorylation | KERKWKCSMCPQAFI CCCCCCCCCCCCCCC | 21.49 | 30619164 | |
601 | Phosphorylation | MCPQAFISPSKLHVH CCCCCCCCHHHEEEE | 19.37 | 25159151 | |
603 | Phosphorylation | PQAFISPSKLHVHFM CCCCCCHHHEEEEEC | 40.85 | 22210691 | |
638 | Ubiquitination | SNLRTHLKIHTGQKN HHHHHHEEEECCCCC | 25.49 | - | |
646 | Phosphorylation | IHTGQKNYRCTLCDK EECCCCCEEEEECCC | 17.69 | - | |
678 | Phosphorylation | EKNLKCDYCDKLFMR CCCCCCCCCCHHHHC | 16.42 | - | |
723 | Phosphorylation | HLKKHLNSHEGKRDY HHHHHHHCCCCCCHH | 29.31 | - | |
756 | Phosphorylation | LKTCKGPTSSSSAPE HHCCCCCCCCCCCCH | 50.32 | 28111955 | |
757 | Phosphorylation | KTCKGPTSSSSAPEE HCCCCCCCCCCCCHH | 31.21 | 28111955 | |
758 | Phosphorylation | TCKGPTSSSSAPEEE CCCCCCCCCCCCHHH | 30.69 | 28111955 | |
759 | Phosphorylation | CKGPTSSSSAPEEEE CCCCCCCCCCCHHHC | 30.22 | 28111955 | |
760 | Phosphorylation | KGPTSSSSAPEEEEE CCCCCCCCCCHHHCC | 50.20 | 28111955 | |
770 | Phosphorylation | EEEEEDDSEEEDLAD HHHCCCCCCCHHHHH | 60.26 | 26657352 | |
778 | Phosphorylation | EEEDLADSVGTEDCR CCHHHHHHCCCCCHH | 19.48 | 28111955 | |
781 | Phosphorylation | DLADSVGTEDCRINS HHHHHCCCCCHHHCC | 26.88 | 28111955 | |
788 | Phosphorylation | TEDCRINSAVYSADE CCCHHHCCEEEECCH | 19.42 | 23312004 | |
791 | Phosphorylation | CRINSAVYSADESLS HHHCCEEEECCHHHH | 9.62 | 23312004 | |
792 | Phosphorylation | RINSAVYSADESLSA HHCCEEEECCHHHHC | 23.73 | 28985074 | |
796 | Phosphorylation | AVYSADESLSAHK-- EEEECCHHHHCCC-- | 28.33 | 23312004 | |
798 | Phosphorylation | YSADESLSAHK---- EECCHHHHCCC---- | 37.29 | 23312004 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of PRDM4_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of PRDM4_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of PRDM4_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
PRDM4_HUMAN | PRDM4 | physical | 20211142 | |
SRTD1_HUMAN | SERTAD1 | physical | 20211142 | |
HDAC3_HUMAN | HDAC3 | physical | 15051733 | |
HDAC2_HUMAN | HDAC2 | physical | 15051733 | |
HDAC1_HUMAN | HDAC1 | physical | 15051733 | |
CTBL1_HUMAN | CTNNBL1 | physical | 25416956 | |
MSRB3_HUMAN | MSRB3 | physical | 25416956 |
Kegg Disease | ||||||
---|---|---|---|---|---|---|
There are no disease associations of PTM sites. | ||||||
OMIM Disease | ||||||
There are no disease associations of PTM sites. | ||||||
Kegg Drug | ||||||
There are no disease associations of PTM sites. | ||||||
DrugBank | ||||||
There are no disease associations of PTM sites. |
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