PRDM4_HUMAN - dbPTM
PRDM4_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRDM4_HUMAN
UniProt AC Q9UKN5
Protein Name PR domain zinc finger protein 4
Gene Name PRDM4
Organism Homo sapiens (Human).
Sequence Length 801
Subcellular Localization Nucleus .
Protein Description May function as a transcription factor involved in cell differentiation..
Protein Sequence MHHRMNEMNLSPVGMEQLTSSSVSNALPVSGSHLGLAASPTHSAIPAPGLPVAIPNLGPSLSSLPSALSLMLPMGIGDRGVMCGLPERNYTLPPPPYPHLESSYFRTILPGILSYLADRPPPQYIHPNSINVDGNTALSITNNPSALDPYQSNGNVGLEPGIVSIDSRSVNTHGAQSLHPSDGHEVALDTAITMENVSRVTSPISTDGMAEELTMDGVAGEHSQIPNGSRSHEPLSVDSVSNNLAADAVGHGGVIPMHGNGLELPVVMETDHIASRVNGMSDSALSDSIHTVAMSTNSVSVALSTSHNLASLESVSLHEVGLSLEPVAVSSITQEVAMGTGHVDVSSDSLSFVSPSLQMEDSNSNKENMATLFTIWCTLCDRAYPSDCPEHGPVTFVPDTPIESRARLSLPKQLVLRQSIVGAEVGVWTGETIPVRTCFGPLIGQQSHSMEVAEWTDKAVNHIWKIYHNGVLEFCIITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQIGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQGHSGSHGPSHSKERKWKCSMCPQAFISPSKLHVHFMGHMGMKPHKCDFCSKAFSDPSNLRTHLKIHTGQKNYRCTLCDKSFTQKAHLESHMVIHTGEKNLKCDYCDKLFMRRQDLKQHVLIHTQERQIKCPKCDKLFLRTNHLKKHLNSHEGKRDYVCEKCTKAYLTKYHLTRHLKTCKGPTSSSSAPEEEEEDDSEEEDLADSVGTEDCRINSAVYSADESLSAHK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
198PhosphorylationAITMENVSRVTSPIS
EEEEECCCCCCCCCC		32.39-
201PhosphorylationMENVSRVTSPISTDG
EECCCCCCCCCCCCC		27.8929978859
202PhosphorylationENVSRVTSPISTDGM
ECCCCCCCCCCCCCC		19.8527050516
205PhosphorylationSRVTSPISTDGMAEE
CCCCCCCCCCCCCCE		24.6729978859
206PhosphorylationRVTSPISTDGMAEEL
CCCCCCCCCCCCCEE		36.9722115753
412UbiquitinationRARLSLPKQLVLRQS
HHCCCCCHHHHHHHH		62.6521890473
447PhosphorylationGPLIGQQSHSMEVAE
HHHCCCCCCCCHHHH		15.0528509920
593PhosphorylationKERKWKCSMCPQAFI
CCCCCCCCCCCCCCC		21.4930619164
601PhosphorylationMCPQAFISPSKLHVH
CCCCCCCCHHHEEEE		19.3725159151
603PhosphorylationPQAFISPSKLHVHFM
CCCCCCHHHEEEEEC		40.8522210691
638UbiquitinationSNLRTHLKIHTGQKN
HHHHHHEEEECCCCC		25.49-
646PhosphorylationIHTGQKNYRCTLCDK
EECCCCCEEEEECCC		17.69-
678PhosphorylationEKNLKCDYCDKLFMR
CCCCCCCCCCHHHHC		16.42-
723PhosphorylationHLKKHLNSHEGKRDY
HHHHHHHCCCCCCHH		29.31-
756PhosphorylationLKTCKGPTSSSSAPE
HHCCCCCCCCCCCCH		50.3228111955
757PhosphorylationKTCKGPTSSSSAPEE
HCCCCCCCCCCCCHH		31.2128111955
758PhosphorylationTCKGPTSSSSAPEEE
CCCCCCCCCCCCHHH		30.6928111955
759PhosphorylationCKGPTSSSSAPEEEE
CCCCCCCCCCCHHHC		30.2228111955
760PhosphorylationKGPTSSSSAPEEEEE
CCCCCCCCCCHHHCC		50.2028111955
770PhosphorylationEEEEEDDSEEEDLAD
HHHCCCCCCCHHHHH		60.2626657352
778PhosphorylationEEEDLADSVGTEDCR
CCHHHHHHCCCCCHH		19.4828111955
781PhosphorylationDLADSVGTEDCRINS
HHHHHCCCCCHHHCC		26.8828111955
788PhosphorylationTEDCRINSAVYSADE
CCCHHHCCEEEECCH		19.4223312004
791PhosphorylationCRINSAVYSADESLS
HHHCCEEEECCHHHH		9.6223312004
792PhosphorylationRINSAVYSADESLSA
HHCCEEEECCHHHHC		23.7328985074
796PhosphorylationAVYSADESLSAHK--
EEEECCHHHHCCC--		28.3323312004
798PhosphorylationYSADESLSAHK----
EECCHHHHCCC----		37.2923312004
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRDM4_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRDM4_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRDM4_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRDM4_HUMANPRDM4physical
20211142
SRTD1_HUMANSERTAD1physical
20211142
HDAC3_HUMANHDAC3physical
15051733
HDAC2_HUMANHDAC2physical
15051733
HDAC1_HUMANHDAC1physical
15051733
CTBL1_HUMANCTNNBL1physical
25416956
MSRB3_HUMANMSRB3physical
25416956
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRDM4_HUMAN

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory