PCNA1_ARATH - dbPTM
PCNA1_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PCNA1_ARATH
UniProt AC Q9M7Q7
Protein Name Proliferating cellular nuclear antigen 1
Gene Name PCNA
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 263
Subcellular Localization Nucleus.
Protein Description This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand..
Protein Sequence MLELRLVQGSLLKKVLESIKDLVNDANFDCSSTGFSLQAMDSSHVALVSLLLRSEGFEHYRCDRNLSMGMNLGNMSKMLKCAGNDDIITIKADDGGDTVTFMFESPTQDKIADFEMKLMDIDSEHLGIPDAEYHSIVRMPSNEFSRICKDLSSIGDTVVISVTKEGVKFSTAGDIGTANIVLRQNTTVDKPEDAIVIEMKEPVSLSFALRYMNSFTKATPLSDTVTISLSSELPVVVEYKVAEMGYIRYYLAPKIEEEEDTNP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
13SumoylationLVQGSLLKKVLESIK
HHCHHHHHHHHHHHH
46.24-
14SumoylationVQGSLLKKVLESIKD
HCHHHHHHHHHHHHH
52.61-
20SumoylationKKVLESIKDLVNDAN
HHHHHHHHHHHHHCC
55.05-
217SumoylationRYMNSFTKATPLSDT
HHHHCCCCCCCCCCE
48.53-
240SumoylationLPVVVEYKVAEMGYI
CCEEEEEEEECCCCE
22.82-
254SumoylationIRYYLAPKIEEEEDT
EEEEECCCCCCCCCC
58.08-
261PhosphorylationKIEEEEDTNP-----
CCCCCCCCCC-----
53.3125561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PCNA1_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PCNA1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PCNA1_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DPOD1_ARATHEMB2780physical
20706207
PCNA2_ARATHPCNA2physical
20706207
DPOD2_ARATHPOLD2physical
20706207
Y3440_ARATHAT4G34400physical
20706207
UBQ3_ARATHUBQ3physical
23314815
PCNA2_ARATHPCNA2physical
23656863
SUMO3_ARATHSUMO3physical
20855607
SUMO1_ARATHSUMO1physical
20855607
PCNA1_ARATHPCNA1physical
19388052
CDN1A_HUMANCDKN1Aphysical
19388052

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PCNA1_ARATH

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Related Literatures of Post-Translational Modification

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